Delayed Hypersensitivity Reactions Following First Dose of the SARS-CoV2 mRNA Vaccines

• Type of Material: Article
• Authors: Jennifer Xu, Emory University; Kristine Vanijcharoenkarn, Emory University; Marybeth Sexton, Emory University; Lindsay Martin, Emory University; Frances Eun-Hyung Lee, Emory University; Merin Elizabeth Kuruvilla, Emory University
• Language: English
• Date: 2021-07-21
• Publisher: SPRINGER
• Publication Version: Final Published Version
• Copyright Statement: © Society of General Internal Medicine 2021
• License: Creative Commons Attribution 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.1007/s11606-021-07015-w
• Title of Journal or Parent Work: JOURNAL OF GENERAL INTERNAL MEDICINE
• Volume: 36
• Issue: 10
• Start Page: 3298
• End Page: 3300
• Keywords: Medicine, General & Internal; Science & Technology; General & Internal Medicine; Life Sciences & Biomedicine; Health Care Sciences & Services
• Research Categories: Health Sciences, Medicine and Surgery

Abstract

Vaccination is crucial to curtail the spread of SARS-CoV2; however, reports of adverse reactions including allergic reactions have increased public fears of the vaccine.1 The incidence of true hypersensitivity including both immediate and delayed reactions is estimated at ~13 cases per million.2 Delayed allergic reactions are heterogeneous, and there are limited reports regarding delayed reactions to the SARS-CoV2 mRNA vaccines.