Population and Individual-Level Effects of Human Immunodeficiency Virus Preexposure Prophylaxis on Sexually Transmitted Infection Epidemics Among Men Who Have Sex With Men.

• Type of Material: Article
• Authors: Jeremy Grey, Emory University; Elizabeth A Torrone, Centers for Disease Control and Prevention; Patrick Sullivan, Emory University; Kevin M Weiss, Emory University; Sevgi O Aral, Centers for Disease Control and Prevention
• Language: English
• Date: 2019-12
• Publisher: American Sexually Transmitted Diseases Association
• Publication Version: Author Accepted Manuscript (After Peer Review)
• Copyright Statement: © 2019 American Sexually Transmitted Diseases Association. All rights reserved.
• Final Published Version (URL): http://dx.doi.org/10.1097/OLQ.0000000000001080
• Title of Journal or Parent Work: Sex Transm Dis
• Volume: 46
• Issue: 12
• Start Page: 759
• End Page: 761
• Keywords: Public Health; Humans; Pre-Exposure Prophylaxis; Female; Male; Sexual and Gender Minorities; United States; Homosexuality, Male; Sexually Transmitted Diseases; HIV Infections

Abstract

Human immunodeficiency virus (HIV) preexposure prophylaxis (HIV PrEP)1 provides substantial individual-level HIV risk reduction and may confer a population-level decrease in HIV incidence among gay, bisexual, and other men who have sex with men (MSM) when high HIV PrEP coverage is obtained.2 Unfortunately, the effect of HIV PrEP on sexually transmitted infection (STI) epidemics among MSM is less clear. We review recent trends in reported STIs among MSM in the United States, discuss the mechanisms by which HIV PrEP may impact STI rates, and consider the resulting population and individual-level effects of HIV PrEP on STI epidemics.