Survival of Infants Born at Periviable Gestational Ages

• Type of Material: Article
• Authors: Ravi Mangal Patel, Emory University; Matthew A. Rysavy, University of Wisconsin; Edward F. Bell, University of Iowa; Jon E. Tyson, University of Texas
• Language: English
• Date: 2017-06-01
• Publisher: Elsevier: 12 months
• Publication Version: Author Accepted Manuscript (After Peer Review)
• Copyright Statement: © 2017 Elsevier Inc.
• Final Published Version (URL): http://dx.doi.org/10.1016/j.clp.2017.01.009
• Title of Journal or Parent Work: Clinics in Perinatology
• ISSN: 0095-5108
• Volume: 44
• Issue: 2
• Start Page: 287
• End Page: 303
• Grant/Funding Information: The review was supported, in part, by the National Institutes of Health under award K23 HL128942 (R.M.P.).
• Keywords: DELIVERY ROOM; Resuscitation; EXTREMELY PRETERM INFANTS; ROOM CARDIOPULMONARY-RESUSCITATION; NEONATAL INTENSIVE-CARE; POPULATION-BASED COHORT; Stillbirth; Mortality; EXTREMELY PREMATURE-INFANTS; Pediatrics; Preterm infant; Obstetrics & Gynecology; Science & Technology; LOW-BIRTH-WEIGHT; Perinatal epidemiology; EXTREME PREMATURITY; RESEARCH NETWORK; Life Sciences & Biomedicine; OF-LIFE DECISIONS
• Research Categories: Health Sciences, Obstetrics and Gynecology

Abstract

Periviable births are those occurring from 20 0/7 through 25 6/7 weeks of gestation. Among and within developed nations, significant variation exists in the approach to obstetric and neonatal care for periviable birth. Understanding gestational age–specific survival, including factors that may influence survival estimates and how these estimates have changed over time, may guide approaches to the care of periviable births and inform conversations with families and caregivers. This review provides a historical perspective on survival following periviable birth, summarizes recent and new data on gestational age–specific survival rates, and addresses factors that have a significant impact on survival.