The long-term effects of maternal depression: Early childhood physical health as a pathway to offspring depression

• Type of Material: Article
• Authors: Elizabeth Raposa, University of California, Los Angeles; Constance Hammen, University of California, Los Angeles; Patricia Brennan, Emory University; Jake Najman, University of Queensland
• Language: English
• Date: 2014-01-01
• Publisher: Elsevier: 12 months
• Publication Version: Author Accepted Manuscript (After Peer Review)
• Copyright Statement: © 2014 Society for Adolescent Health and Medicine. All rights reserved.
• License: Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.1016/j.jadohealth.2013.07.038
• Title of Journal or Parent Work: Journal of Adolescent Health
• ISSN: 1054-139X
• Volume: 54
• Issue: 1
• Start Page: 88
• End Page: 93
• Grant/Funding Information: This research was supported by the National Health and Medical Research Council; the Mater Misericordiae Mother’s Hospital in Queensland, Australia; the National Institute of Mental Health grant R01 MH52239; and an NIMH training grant MH15750 Biobehavioral Issues in Mental and Physical Health (Dr. Stanton & Dr. Dunkel-Schetter).
• Keywords: Mothers; Australia; Young Adult; Pregnancy; Social adjustment; Adult; Adolescent; Community sample; Child and adolescent health; Infant; Child, Preschool; Infant, Newborn; Humans; Pregnancy Complications; Depressive Disorder; Depression; Longitudinal Studies; Female; Surveys and Questionnaires
• Research Categories: Psychology, Developmental; Health Sciences, Mental Health; Psychology, Clinical

Abstract

Purpose: Cross-sectional and retrospective studies have highlighted the long-term negative effects of maternal depression on offspring physical, social, and emotional development, but longitudinal research is needed to clarify the pathways by which maternal depression during pregnancy and early childhood affects offspring outcomes. The current study tested one developmental pathway by which maternal depression during pregnancy might negatively impact offspring mental health in young adulthood, via poor physical health in early childhood. Methods: The sample consisted of 815 Australian youth and their mothers who were followed for 20 years. Mothers reported on their own depressive symptoms during pregnancy and offspring early childhood. Youth completed interviews about health-related stress and social functioning at age 20 years, and completed a questionnaire about their own depressive symptoms 2 to 5 years later. Results: Path analysis indicated that prenatal maternal depressive symptoms predicted worse physical health during early childhood for offspring, and this effect was partially explained by ongoing maternal depression in early childhood. Offspring poor physical health during childhood predicted increased health-related stress and poor social functioning at age 20. Finally, increased health-related stress and poor social functioning predicted increased levels of depressive symptoms later in young adulthood. Maternal depression had a significant total indirect effect on youth depression via early childhood health and its psychosocial consequences. Conclusions: Poor physical health in early childhood and its effects on young adults' social functioning and levels of health related stress is one important pathway by which maternal depression has long-term consequences for offspring mental health.