A Review on Antibacterial, Antiviral, and Antifungal Activity of Curcumin

• Type of Material: Article
• Authors: Soheil Zorofchian Moghadamtousi, University of Malaya; Habsah Abdul Kadir, University of Malaya; Pouya Hassandarvish, University of Malaya; Hassan Tajik, Guilan University; Sazaly Abubakar, University of Malaya; Keivan Zandi, Emory University
• Language: English
• Date: 2014-01-01
• Publisher: Hindawi Publishing Corporation
• Publication Version: Final Published Version
• Copyright Statement: © 2014 Soheil Zorofchian Moghadamtousi et al.
• License: Creative Commons Attribution 3.0 Unported
• Final Published Version (URL): http://dx.doi.org/10.1155/2014/186864
• Title of Journal or Parent Work: BioMed Research International
• ISSN: 2314-6133
• Volume: 2014
• Start Page: 186864
• End Page: 186864
• Grant/Funding Information: The authors would like to thank University of Malaya for University Malaya Research Flagship Grant (UMRG) (FL001-13HTM) and Postgraduate Research Grant (PPP) (PG005-2012B).
• Keywords: Biotechnology & Applied Microbiology; CANDIDA-ALBICANS; IN-VITRO; ANTIMICROBIAL ACTIVITY; COXSACKIEVIRUS B3 REPLICATION; CLINICAL INTEREST; VIRUS-REPLICATION; Science & Technology; Life Sciences & Biomedicine; Research & Experimental Medicine; BIOLOGICAL-ACTIVITIES; CONSTITUTIVE ACTIVATION; NF-KAPPA-B; LONG TERMINAL REPEAT; Medicine, Research & Experimental
• Research Categories: Health Sciences, Epidemiology; Biology, Microbiology

Abstract

Curcuma longa L. (Zingiberaceae family) and its polyphenolic compound curcumin have been subjected to a variety of antimicrobial investigations due to extensive traditional uses and low side effects. Antimicrobial activities for curcumin and rhizome extract of C. longa against different bacteria, viruses, fungi, and parasites have been reported. The promising results for antimicrobial activity of curcumin made it a good candidate to enhance the inhibitory effect of existing antimicrobial agents through synergism. Indeed, different investigations have been done to increase the antimicrobial activity of curcumin, including synthesis of different chemical derivatives to increase its water solubility as well ass cell up take of curcumin. This review aims to summarize previous antimicrobial studies of curcumin towards its application in the future studies as a natural antimicrobial agent.