Characteristics of Patients Undergoing Endoscopic Retrograde Cholangiopancreatography for Sphincter of Oddi Disorders

• Type of Material: Article
• Authors: Gregory A Cote, Medical University of South Carolina; Haley Nitchie, Medical University of South Carolina; Joseph B Elmunzer, Medical University of South Carolina; Richard S Kwon, University of Michigan; Field Willingham, Emory University; Sachin Wani, University of Colorado Anschutz Medical Campus; Daniel Mullady, Washington University; Amitabh Chak, Case Western Reserve University; Vikesh Singh, Johns Hopkins Medical Institutions, Baltimore; Adam Slivka, University of Pittsburgh; Shyam Varadarajulu, Advent Health, Orlando; Martin Freeman, University of Minnesota, Minneapolis; Srinivas Gaddam, Cedars Sinai School of Medicine; Priya Jamidar, Yale University; Paul Tarnasky, Methodist Digestive Institute; Lydia Foster, Medical University of South Carolina; Peter B Cotton, Medical University of South Carolina
• Language: English
• Date: 2022-03-01
• Publisher: ELSEVIER SCIENCE INC
• Publication Version: Author Accepted Manuscript (After Peer Review)
• Copyright Statement: © 2022 by the AGA Institute
• License: Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.1016/j.cgh.2021.03.008
• Title of Journal or Parent Work: CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
• Volume: 20
• Issue: 3
• Start Page: E627
• End Page: E634
• Grant/Funding Information: Research reported in this publication was supported by the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health award R01DK115495 (G.A.C., L.F., and P.B.C.). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
• Keywords: DYSFUNCTION; ERCP; Functional GI Disorders; PAIN; Life Sciences & Biomedicine; Gastroenterology & Hepatology; SUSPECTED SPHINCTER; Sphincter of Oddi Dysfunction; GALLBLADDER; DISABILITY; Science & Technology; Sphincterotomy

Abstract

The concept that sphincter of Oddi dysfunction (SOD) can cause attacks of biliary-type pain in postcholecystectomy patients and those with unexplained recurrent acute pancreatitis, and that endoscopic sphincterotomy can ameliorate symptoms, remains unproven. The Evaluating Predictors and Interventions in Sphincter of Oddi Dysfunction (EPISOD) study of patients without objective evidence for biliary obstruction showed no difference in outcomes between those who underwent sphincterotomy or sham treatment.1 To date, there have been no studies examining the characteristics of patients who still are being offered endoscopic retrograde cholangiopancreatography (ERCP) for SOD since the EPISOD publication, although the absolute number appears to have declined.2.