Retraction Note: OCT4 as a target of miR-34a stimulates p63 but inhibits p53 to promote human cell transformation(Cell Death Dis, (2014), 10.1038/cddis.2013.563)

• Type of Material: Article
• Authors: WL Ng, Emory University; Guangnan Chen, Emory University; M Wang, Universities Space Research Association; H Wang, Emory University; M Story, UT Southwestern Medical Center; JW Shay, UT Southwestern Medical Center; X Zhang, Emory University; J Wang, Emory University; ARMR Amin, Emory University; B Hu, Emory University; FA Cucinotta, University of Nevada, Las Vegas; Ya Wang, Emory University
• Language: English
• Date: 2022-03-01
• Publisher: Springer Nature
• Publication Version: Final Published Version
• Copyright Statement: © The Author(s) 2022
• License: Creative Commons Attribution 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.1038/s41419-022-04665-4
• Title of Journal or Parent Work: Cell Death and Disease
• Volume: 13
• Issue: 3
• Start Page: 219
• End Page: 219
• Keywords: human cell transformation
• Research Categories: Biology, Cell; Health Sciences, Oncology

Abstract

The Editors-in-Chief have retracted this article because concerns have been raised about the reliability of the presented data. An investigation by the US Office of Research Integrity has concluded that western blot images for total protein expression in human cell lines subject to gene depletion and/or overexpression were produced by reusing immunoblot bands and relabeling them to represent different experiments in seven figure panels in five papers and one grant application. In this article, this affects Fig. 5B, representing p53 and p63 levels in human lung epithelial cells with or without gene depletion. Authors M. Story and J. W. Shay agree to this retraction. Authors Y. Wang and W. L. Ng do not agree to this retraction. Authors A. R. M. R. Amin and F. A. Cucinotta have not responded to any correspondence from the editor or publisher about this retraction. The Publisher has not been able to obtain a current email address for authors G. Chen, M. Wang, H. Wang, X. Zhang, J. Wang and B. Hu.