Pericentral hydroxychloroquine retinopathy in a Caucasian female

• Type of Material: Article
• Authors: Nikhil Anand, Emory University; Robert A. Prinzi, Emory University; Cory Hoeferlin, Emory University School of Medicine; Jiong Yan, Emory University; Nieraj Jain, Emory University
• Language: English
• Date: 2018-03-01
• Publisher: Elsevier
• Publication Version: Final Published Version
• Copyright Statement: © 2018 Published by Elsevier Inc.
• License: Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.1016/j.ajoc.2018.01.019
• Title of Journal or Parent Work: American Journal of Ophthalmology Case Reports
• ISSN: 2451-9936
• Volume: 9
• Start Page: 93
• End Page: 95
• Keywords: Bull's eye maculopathy; Plaquenil; Pericentral; Toxicity; Multifocal electroretinogram; Hydroxychloroquine
• Research Categories: Health Sciences, General; Health Sciences, Medicine and Surgery

Abstract

To report a rare presentation of the pericentral pattern of hydroxychloroquine (HCQ) retinal toxicity in a Caucasian female. Observations: The patient presented with 20 years of exposure to HCQ, at a daily dose of 5.2mg/kg of actual body weight, and manifested a pericentral-only phenotype of HCQ toxicity, as demonstrated with detailed structural and functional testing. Conclusions and importance: Although rare, the pericentral pattern of HCQ toxicity may occur in Caucasian patients in the absence of paracentral changes.