Organophosphate Pesticide Urinary Metabolites Among Latino Immigrants: North Carolina Farmworkers and Non-farmworkers Compared

• Type of Material: Article
• Authors: Thomas A. Arcury, Wake Forest School of Medicine; Paul J. Laurienti, Wake Forest School of Medicine; Haiying Chen, Wake Forest School of Medicine; Timothy D. Howard, Wake Forest School of Medicine; Dana Barr, Emory University; Dana C. Mora, Wake Forest School of Medicine; Phillip Summers, Wake Forest School of Medicine; Sara A. Quandt, Wake Forest School of Medicine
• Language: English
• Date: 2016-11-01
• Publisher: Lippincott, Williams & Wilkins
• Publication Version: Author Accepted Manuscript (After Peer Review)
• Copyright Statement: Copyright © 2016 American College of Occupational and Environmental Medicine. Unauthorized reproduction of this article is prohibited.
• Final Published Version (URL): http://dx.doi.org/10.1097/JOM.0000000000000875
• Title of Journal or Parent Work: Journal of Occupational and Environmental Medicine
• ISSN: 1076-2752
• Volume: 58
• Issue: 11
• Start Page: 1079
• End Page: 1086
• Grant/Funding Information: Funding was provided by grants from the National Institute of Environmental Health Sciences (R01-ES08739).
• Keywords: Life Sciences & Biomedicine; CHILDREN; Farmworkers; Agriculture; PARKINSONS-DISEASE; FARM-WORKERS; POPULATION; Science & Technology; APPLICATORS; Environmental exposures; NEW-YORK-CITY; Occupational exposure; Public, Environmental & Occupational Health; Immigrant health; PRENATAL EXPOSURE; AGRICULTURAL HEALTH; Organophosphate pesticides; VALIDATION; DIALKYLPHOSPHATE METABOLITES
• Research Categories: Health Sciences, Occupational Health and Safety; Health Sciences, Public Health; Environmental Sciences

Abstract

Background: This analysis documents detections and concentrations of the six dialkylphosphate (DAP) urinary metabolite of organophosphorus (OP) pesticides among North Carolina Latino migrant farmworkers, with comparison to non-farmworker Latino immigrants. Methods: Participants provided up to four urine samples during the 2012 and 2013 agricultural seasons. Composite urine samples for each year were analyzed. Results: DAP urinary metabolite detections were similar in farmworkers and non-farmworker; for example, for 2012, 75.4% of farmworkers and 67.4% of nonfarmworkers and, for 2013, 89.3% of farmworkers and 89.7% of nonfarmworkers had dimethylthiophosphate detections. DAP geometric mean concentrations were high; for example, dimethylphosphate concentrations among farmworkers were 11.39mg/g creatinine for 2012 and 4.49μg/g creatinine for 2013, while they were 10.49mg/g creatinine for 2012 and 1.97μg/g creatinine for 2013 for non-farmworkers Conclusions: Research to reduce pesticide exposure among Latino farmworkers and non-farmworkers is needed.