Publication
Do gamma delta T cells predict osteonecrosis of the jaw?
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- Persistent URL
- Last modified
- 05/21/2025
- Type of Material
- Authors
-
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M. Neale Weitzmann, Emory University
- Language
- English
- Date
- 2013-04-01
- Publisher
- Wiley
- Publication Version
- Copyright Statement
- © 2013 American Society for Bone and Mineral Research
- Final Published Version (URL)
- Title of Journal or Parent Work
- ISSN
- 0884-0431
- Volume
- 28
- Issue
- 4
- Start Page
- 723
- End Page
- 727
- Grant/Funding Information
- The author gratefully acknowledges support from the Biomedical Laboratory Research & Development Service of the VA Office of Research and Development (5I01BX000105) and by NIH grants from NIAMS (R01AR056090 and R01AR059364) and the NIA (R01AG040013).
- Abstract
- A large body of evidence has established that T cells and cytokine mediators originating from the immune system potently impact bone turnover in both physiologic and pathologic conditions. Indeed, osteoclasts derive from precursors that circulate within the immune compartment; however, new revelations continue to emerge attesting to the depth of integration of the skeletal and immune systems, and the consequences of the immuno-skeletal interface for bone metabolism.
- Author Notes
- Keywords
- Research Categories
- Health Sciences, Medicine and Surgery
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