Seroprevalence of Antibodies to Avian Influenza A (H5) and A (H9) Viruses among Market Poultry Workers, Hanoi, Vietnam, 2001

• Type of Material: Article
• Authors: Timothy M. Uyeki, Centers for Disease Control and Prevention; Doan Nguyen, Emory University; Thomas Rowe, Centers for Disease Control and Prevention; Xiuhua Lu, Centers for Disease Control and Prevention; Jean Hu-Primmer, Centers for Disease Control and Prevention; Lien P. Huynh, National Institute of Hygiene and Epidemiology; Nguyen L. K. Hang, National Institute of Hygiene and Epidemiology; Jacqueline M. Katz, Centers for Disease Control and Prevention
• Language: English
• Date: 2012-08-21
• Publisher: PUBLIC LIBRARY SCIENCE
• Publication Version: Final Published Version
• Copyright Statement: This is an open-access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.
• License: Creative Commons Universal : Public Domain Dedication
• Final Published Version (URL): http://dx.doi.org/10.1371/journal.pone.0043948
• Title of Journal or Parent Work: PLOS ONE
• Volume: 7
• Issue: 8
• Start Page: e43948
• End Page: e43948
• Grant/Funding Information: This work was supported by the Centers for Disease Control and Prevention (CDC). CDC staff were involved in study design, data collection and analysis, preparation of the manuscript, and decision to publish. No other external funding was received.
• Keywords: Multidisciplinary Sciences; HONG-KONG; RISK-FACTORS; HUMAN INFECTION; VACCINE; CHINA; Science & Technology; HIGHLY PATHOGENIC H5N1; ILLNESS; Science & Technology - Other Topics
• Research Categories: Health Sciences, Pathology; Health Sciences, Immunology

Abstract

Background: The frequency of avian influenza A virus infections among poultry workers is not well understood. Methods: A seroprevalence study of market poultry workers and persons without occupational poultry exposure was conducted during 2001 in Hanoi, Vietnam. Sera were tested for avian influenza H5 and H9 antibodies by microneutralization and Western blot assays. Results: Seroprevalence of H5 and H9 antibodies was 4% and 3% in poultry workers and 1% and 3.5% in non-poultry workers, respectively. Conclusions: Seroprevalence of H5 and H9 antibodies was low among Hanoi market poultry workers in 2001, but can serve as a baseline for additional studies.