Publication

Communicating PNPLA3 genetic risk status for NAFLD among Mexican-origin men

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Last modified
  • 06/25/2025
Type of Material
Authors
    Edgar A Villavicencio, University of ArizonaAdriana Maldonado, University of ArizonaRebecca M Crocker, University of ArizonaYue Guan, Emory UniversityChris Stallman, University of ArizonaDavid O Garcia, University of Arizona
Language
  • English
Date
  • 2023-01-04
Publisher
  • Frontiers Media
Publication Version
Copyright Statement
  • © 2023 Villavicencio, Maldonado, Crocker, Guan, Stallman and Garcia.
License
Final Published Version (URL)
Title of Journal or Parent Work
Volume
  • 10
Grant/Funding Information
  • This work was supported by the National Institute on Minority Health and Health Disparities (award number K01MD014761 to DG), the Emory Cancer Prevention and Control Research Network (CPCRN) (U48 DP006413 to YG), the National Cancer Institute of the National Institutes of Health under the awards for the Partnership of Native American Cancer Prevention U54CA143924 (UACC), and University of Arizona Core Facilities Pilot Program (to DG).
Supplemental Material (URL)
Abstract
  • The burden of non-alcoholic fatty liver disease (NAFLD) continues to disproportionately impact under-resourced communities in the U.S., particularly Mexican-origin populations. Genetic polymorphisms such as the rs738409 C/G variant in patatin-like phospholipase domain-containing 3 (PNPLA3) have been associated with higher prevalence of and progression along the NAFLD spectrum. This qualitative study conducted in the U.S. Southwest aimed to assess Mexican-origin men's experience receiving genetic testing for PNPLA3 risk carrier status.
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Research Categories
  • Health Sciences, Public Health

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