Advances of Cancer Therapy by Nanotechnology

• Type of Material: Article
• Authors: Xu Wang, Emory University; Yiqing Wang, Emory University; Georgia Chen, Emory University; Dong M Shin, Emory University
• Language: English
• Date: 2009-03
• Publisher: Korean Cancer Association
• Publication Version: Final Published Version
• Copyright Statement: © 2009 Korean Cancer Association. Open Access
• Final Published Version (URL): http://e-crt.org/journal/view.php?number=224
• Title of Journal or Parent Work: Cancer Research and Treatment
• ISSN: 1598-2998
• Volume: 41
• Issue: 1
• Start Page: 1
• End Page: 11
• Grant/Funding Information: This work was supported by National Cancer Institute (NCI) Specialized Program of Research Excellence (SPORE) grant (P50CA128613) to D.M. Shin and Centers of Cancer Nanotechnology Excellence (CCNE) grant (U54 CA119338) to D.M. Shin and Z.G. Chen.
• Keywords: Nanoparticels; Drug delivery; Cancer therapy
• Research Categories: Engineering, Biomedical; Health Sciences, Oncology

Abstract

Recent developments in nanotechnology offer researchers opportunities to significantly transform cancer therapeutics. This technology has enabled the manipulation of the biological and physicochemical properties of nanomaterials to facilitate more efficient drug targeting and delivery. Clinical investigations suggest that therapeutic nanoparticles can enhance efficacy and reduced side effects compared with conventional cancer therapeutic drugs. Encouraged by rapid and promising progress in cancer nanotechnology, researchers continue to develop novel and efficacious nanoparticles for drug delivery. The use of therapeutic nanoparticles as unique drug delivery systems will be a significant addition to current cancer therapeutics.