Cortical State Fluctuations across Layers of V1 during Visual Spatial Perception

• Type of Material: Article
• Authors: Anderson Speed, Georgia Institute of Technology; Joseph Del Rosario, Georgia Institute of Technology; Christopher P. Burgess, University College London; Bilal Haider, Emory University
• Language: English
• Date: 2019-03-12
• Publisher: Cell Press
• Publication Version: Author Accepted Manuscript (After Peer Review)
• Copyright Statement: © 2019 The Author(s).
• Final Published Version (URL): http://dx.doi.org/10.1016/j.celrep.2019.02.045
• Title of Journal or Parent Work: Cell Reports
• Volume: 26
• Issue: 11
• Start Page: 2868
• End Page: +
• Grant/Funding Information: Matteo Carandini for generous support in the initial phase of this study (Wellcome Trust Grants 095668 and 095669).; B.H. was funded by the National Science Foundation IRFP, GT Neural Engineering Center, Whitehall Foundation, Sloan Foundation, and National Institute of Neurological Disorders and Stroke (NIH 1R01 NS107968).; J.D.R. was funded by a Goizueta Foundation Fellowship.
• Keywords: Pyramidal cells; Integration; Macaque; Motor; Neurons; Locomotion; Potassium channel; Life Sciences & Biomedicine; Cell Biology; Responses; Cortex; Science & Technology; Attentional modulation
• Research Categories: Engineering, Biomedical; Biology, Neuroscience; Biology, Cell

Abstract

Speed et al. show that visual behavior in mice is strongly influenced by the state of activity in primary visual cortex (V1). Single-trial perceptual accuracy was highly predictable from oscillations in the input layers and from correlations between excitatory neurons.