Longing for HIV protection

• Type of Material: Article
• Authors: Michelle Zanoni, Emory University; David Palesch, Emory University; Guido Silvestri, Emory University
• Language: English
• Date: 2018-06-01
• Publisher: Nature Research (part of Springer Nature)
• Publication Version: Author Accepted Manuscript (After Peer Review)
• Copyright Statement: © 2018 The Publisher.
• Final Published Version (URL): http://dx.doi.org/10.1038/s41564-018-0169-8
• Title of Journal or Parent Work: Nature Microbiology
• ISSN: 2058-5276
• Volume: 3
• Issue: 6
• Start Page: 648
• End Page: 649
• Keywords: Science & Technology; Life Sciences & Biomedicine; VIREMIA; Microbiology
• Research Categories: Biology, Microbiology; Health Sciences, Public Health; Health Sciences, Pathology

Abstract

Antibodies that potently neutralize highly diverse HIV-1 variants offer great potential for therapy and prevention. Passive administration of HIV-specific neutralizing antibodies genetically modified to have a long serum half-life has now been shown to confer long-lasting protection from infection in the rhesus macaque model.