Clinical Experience of a Novel Optical Coherence Tomography-Guided Coronary Chronic Total Occlusion Re-Entry Device

• Type of Material: Article
• Authors: Pratik Sandesara, Emory University; Gregory C. Robertson, Emory University; Kin F. Chan, Simpson Interventions, Inc.; Douglas Rowe, Simpson Interventions, Inc.; Adrian Ebner, Sanatorio Italiano; Laura Minarsch, MMC Medical; William Lombardi, University of Washington, Seattle; David E. Kandzari, Piedmont Heart Institute; Tomoaki Hinohara, Sequoia Hospital; John B. Simpson, Simpson Interventions, Inc.
• Language: English
• Date: 2023-10-06
• Publisher: Elsevier
• Publication Version: Final Published Version
• Copyright Statement: © 2023 The Authors
• License: Creative Commons Attribution 4.0 International
• Final Published Version (URL): https://doi.org/10.1016/j.jaccas.2023.102041
• Title of Journal or Parent Work: JACC: Case Reports
• Volume: 26
• Start Page: 102041
• Grant/Funding Information: This work was funded by Simpson Interventions, Inc. Drs Sandesara, Robertson, Ebner, Lombardi, Kandzari, and Hinohara and Ms Minarsch are consultants for Simpson Interventions.
• Keywords: image augmentation; guidewire; image-guided intervention; intravascular imaging; chronic total occlusion; optical coherence tomography; percutaneous coronary intervention; antegrade dissection and re-entry; catheter
• Research Categories: Engineering, Biomedical; Health Sciences, Medicine and Surgery

Abstract

We demonstrated a first-in-human case of successful antegrade dissection and re-entry using an image-guided re-entry catheter that enables real-time high-resolution visualization with graphical augmentation, and precision steering and advancement of a guidewire. The total time from over-the-wire deployment in the proximity of the distal cap to successful re-entry was <20 minutes. (Level of Difficulty: Advanced.)