Ethnic differences between Asians and non-Asians in clustering-based phenotype classification of adult-onset diabetes mellitus: A systematic narrative review

• Type of Material: Article
• Authors: Jithin Sam Varghese, Emory University; K.M. Venkat Narayan, Emory University
• Language: English
• Date: 2022-09-23
• Publisher: Elsevier
• Publication Version: Author Accepted Manuscript (After Peer Review)
• Copyright Statement: © 2022 Primary Care Diabetes Europe. Published by Elsevier Ltd. All rights reserved.
• License: Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International
• Final Published Version (URL): https://doi.org/10.1016/j.pcd.2022.09.007
• Title of Journal or Parent Work: Primary Care Diabetes
• Volume: 16
• Issue: 6
• Start Page: 853
• End Page: 856
• Grant/Funding Information: KM Venkat Narayan is supported by National Institutes of Health grants 2P30DK111024-06 and 3P30DK111024-05S1.
• Keywords: cluster analysis; subgroups; Asian; diabetes phenotypes
• Research Categories: Health Sciences, Medicine and Surgery; Health Sciences, Epidemiology

Abstract

Several international studies have stratified people with diabetes into phenotypical clusters. However, there has not been a systematic examination of the variation in these clusters across ethnic groups. For example, some clusters appear more frequent among Asians and may have lower weight, age at diagnosis and poorer beta cell function.