Randomized Clinical Trial of Therapeutic Music Video Intervention for Resilience Outcomes in Adolescents/Young Adults Undergoing Hematopoietic Stem Cell Transplant

• Type of Material: Article
• Authors: Sheri L. Robb, Indiana University; Debra S. Burns, Indiana University–Purdue University Indianapolis; Kristin A. Stegenga, Children’s Mercy Hospitals and Clinics; Paul R. Haut, Indiana University; Patrick O. Monahan, Indiana University; Jane Meza, University of Nebraska Medical Center; Timothy E. Stump, Indiana University; Brooke Cherven, Emory University; Sharron L. Docherty, Duke University; Verna L. Hendricks-Ferguson, St Louis University; Eileen K. Kintner, University of Texas Austin; Ann E Haight, Emory University; Donna A. Wall, University of Manitoba/Cancer Care Manitoba; Joan E. Haase, Indiana University
• Language: English
• Date: 2014-03-15
• Publisher: Wiley: 12 months
• Publication Version: Author Accepted Manuscript (After Peer Review)
• Copyright Statement: © 2013 American Cancer Society.
• Final Published Version (URL): http://dx.doi.org/10.1002/cncr.28355
• Title of Journal or Parent Work: Cancer
• ISSN: 0008-543X
• Volume: 120
• Issue: 6
• Start Page: 909
• End Page: 917
• Grant/Funding Information: National Institute of Nursing Research R01NR008583; National Cancer Institute U10CA098543; U10CA095861.
• Keywords: CANCER; SUPPORT; PSYCHOLOGICAL DISTRESS; music therapy; CHILDREN; TIME; family relations; Life Sciences & Biomedicine; courageous coping; Oncology; cancer; self-transcendence; SURVIVORS; music; BONE-MARROW TRANSPLANTATION; STRATEGIES; Science & Technology; BEHAVIORAL INTERVENTION; social environment; resilience; young adult; PARENTAL PERSPECTIVES; adolescents
• Research Categories: Health Sciences, Nursing; Health Sciences, Oncology

Abstract

BACKGROUND To reduce the risk of adjustment problems associated with hematopoietic stem cell transplant (HSCT) for adolescents/young adults (AYAs), we examined efficacy of a therapeutic music video (TMV) intervention delivered during the acute phase of HSCT to: 1) increase protective factors of spiritual perspective, social integration, family environment, courageous coping, and hope-derived meaning; 2) decrease risk factors of illness-related distress and defensive coping; and 3) increase outcomes of self-transcendence and resilience. METHODS This was a multisite randomized, controlled trial (COG-ANUR0631) conducted at 8 Children's Oncology Group sites involving 113 AYAs aged 11-24 years undergoing myeloablative HSCT. Participants, randomized to the TMV or low-dose control (audiobooks) group, completed 6 sessions over 3 weeks with a board-certified music therapist. Variables were based on Haase's Resilience in Illness Model (RIM). Participants completed measures related to latent variables of illness-related distress, social integration, spiritual perspective, family environment, coping, hope-derived meaning, and resilience at baseline (T1), postintervention (T2), and 100 days posttransplant (T3). RESULTS At T2, the TMV group reported significantly better courageous coping (Effect Size [ES], 0.505; P =.030). At T3, the TMV group reported significantly better social integration (ES, 0.543; P =.028) and family environment (ES, 0.663; P =.008), as well as moderate nonsignificant effect sizes for spiritual perspective (ES, 0.450; P =.071) and self-transcendence (ES, 0.424; P =.088). CONCLUSIONS The TMV intervention improves positive health outcomes of courageous coping, social integration, and family environment during a high-risk cancer treatment. We recommend the TMV be examined in a broader population of AYAs with high-risk cancers. Cancer 2014;120:909-917. © 2013 American Cancer Society. Adolescents/young adults undergoing stem cell transplant for cancer who received a therapeutic music video intervention demonstrated significant posttransplant improvement in resilience-related outcomes of courageous coping, family support/communication, and social support from friends and health care providers.