ACR Appropriateness Criteria (R) Hodgkin Lymphoma-Favorable Prognosis Stage I and II

• Type of Material: Article
• Authors: Sughosh Dhakal, University of Rochester; Ranjana Advani, Stanford Cancer Institute; Leslie K. Ballas, University of Southern California; Bouthaina S. Dabaja, University of Texas MD Anderson Cancer Center; Christopher Flowers, Emory University; Chul S. Ha, University of Texas Health Science Center at San Antonio; Bradford S. Hoppe, University of Florida; Nancy P. Mendenhall, University of Florida; Monika L. Metzger, St Jude Childrens Research Hospital; John P. Plastaras, University of Pennsylvania; Kenneth B. Roberts, Yale University; Ronald Shapiro, Indiana University; Sonali M. Smith, University of Chicago; Stephanie A. Terezakis, Johns Hopkins University Hospital; Karen M. Winkfield, Massachusetts General Hospital; Anas Younes, Memorial Sloan Kettering Cancer Center; Louis S. Constine, University of Rochester
• Language: English
• Date: 2016-12-01
• Publisher: Lippincott Williams & Wilkins
• Publication Version: Author Accepted Manuscript (After Peer Review)
• Copyright Statement: © 2016 American College of Radiology (ACR).
• License: Creative Commons Attribution-NonCommercial 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.1097/COC.0000000000000331
• Title of Journal or Parent Work: American Journal of Clinical Oncology
• Volume: 39
• Issue: 6
• Start Page: 535
• End Page: 544
• Grant/Funding Information: None declared
• Keywords: Science & Technology; Randomized trials; Consolidation radiation; Combined modality therapy; Hodgkin lymphoma; Collaborative British cohort; appropriateness criteria; Radiation therapy; Oncology; combined modality therapy; Positron emission tomography; European organization; 2ND Malignancy; Node radiotherapy; Life Sciences & Biomedicine; Involved field radiotherapy
• Research Categories: Health Sciences, Oncology; Health Sciences, Rehabilitation and Therapy; Health Sciences, Radiology

Abstract

This topic addresses the treatment of newly diagnosed patients with favorable prognosis stage I and II Hodgkin lymphoma. In most cases, combined modality therapy (chemotherapy followed by involved site radiation therapy) constitutes the current standard of care. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision include an extensive analysis of current medical literature from peer-reviewed journals and the application of well-established methodologies (RAND/UCLA Appropriateness Method and Grading of Recommendations Assessment, Development, and Evaluation or GRADE) to rate the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where evidence is lacking or equivocal, expert opinion may supplement the available evidence to recommend imaging or treatment. By combining the most recent medical literature and expert opinion, this revised guideline can aid clinicians in the appropriate use of combined modality therapy for favorable prognosis stage I and II Hodgkin lymphoma. Increasing information about the late effects of treatment has led to attempts to decrease toxicity by using less chemotherapy (decreased duration and/or intensity or different agents) and less radiation therapy (reduced volume and/or dose) while maintaining excellent efficacy.