Covarying ionic conductances to emulate phase maintenance in stomatogastric neurons

• Type of Material: Article
• Authors: Wafa Soofi, Emory University; Astrid A Prinz, Emory University
• Language: English
• Date: 2010-07-20
• Publisher: BioMed Central
• Publication Version: Final Published Version
• Copyright Statement: ©2010 Soofi and Prinz; licensee BioMed Central Ltd.
• License: Creative Commons Attribution 2.0 Generic
• Final Published Version (URL): http://www.biomedcentral.com/1471-2202/11/S1/P60
• Title of Journal or Parent Work: BMC Neurology
• ISSN: 1471-2377
• Volume: 11
• Issue: Suppl 1
• Start Page: P60
• End Page: P60
• Research Categories: Engineering, Biomedical; Biology, General

Abstract

Neuronal networks produce reliable functional output throughout the lifespan of an animal despite ceaseless molecular turnover and a constantly changing environment. Central pattern generators, such as that of the crustacean stomatogastric ganglion (STG), robustly maintain their functionality over a wide range of burst periods [1]. Extracellular recordings of the LP neuron of the STG have demonstrated that as the burst period varies over time, the interspike intervals change proportionally, so that the spike phases are relatively invariant.