Gram-positive diplococci in a cerebrospinal fluid gram stain

• Type of Material: Article
• Authors: Jennifer P. Collins, Emory University; Lars Westblade, Emory University; Evan Anderson, Emory University
• Language: English
• Date: 2016-01-01
• Publisher: Oxford University Press (OUP)
• Publication Version: Final Published Version
• Copyright Statement: © The Author 2016. Published by Oxford University Press on behalf of the Infectious Diseases Society of America.
• License: Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.1093/ofid/ofw206
• Title of Journal or Parent Work: Open Forum Infectious Diseases
• ISSN: 2328-8957
• Volume: 3
• Issue: 4
• Start Page: ofw206
• End Page: ofw206
• Keywords: Meningitis; Gram stain; Pediatrics; Streptococcus pneumoniae
• Research Categories: Health Sciences, Public Health; Health Sciences, Immunology; Health Sciences, General

Abstract

A 5-month-old girl presented with meningitis after receiving amoxicillin for bilateral otitis media. The cerebrospinal fluid (CSF) Gram stain suggested Streptococcus pneumoniae: Gram-positive diplococci with a surrounding clear area indicative of a bacterial capsule. Her CSF and blood cultures grew penicillin-resistant S pneumoniae serotype 35B. This serotype is not included in the 13-valent pneumococcal conjugate vaccine (PCV-13) and has been identified as a cause of invasive pneumococcal disease in the post-PCV-13 era.