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Commentary: Genomic, epigenomic, and transcriptomic signatures of prostate cancer between African American and European American patients

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Last modified
  • 06/17/2025
Type of Material
Authors
    Francois Rollin, Emory UniversitySudarshan Krishnamurthy, Wake Forest UniversitySurabhi Beriwal, Emory University
Language
  • English
Date
  • 2023-08-22
Publisher
  • Frontiers
Publication Version
Copyright Statement
  • © 2023 Rollin, Krishnamurthy and Beriwal
License
Final Published Version (URL)
Title of Journal or Parent Work
Volume
  • 13
Start Page
  • 1218669
Abstract
  • The recent review article by Stevens and colleagues (February 28) (1) explores the genomic, epigenomic, and transcriptomic signatures of prostate cancer in racialized groups. We agree that racial inequities in prostate cancer incidence and outcome need to be described and urgently addressed in order to achieve health equity. However, we have several concerns regarding the methods used and the possible implications of inherent genetic racial differences. We recognize that the appropriate use of race in research is complicated and that we are all learning to do this better with the shared goal of reducing health disparities. Since racial categories are socio-political constructs and poor proxies for human genetic variation (2, 3), the rationale for the use of these categories must be clearly explained in the methods to avoid inadvertently perpetuating the myth of race as an inherent biological category.
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Research Categories
  • Health Sciences, Oncology

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