Publication

The relevance of aging-related changes in brain function to rehabilitation in aging-related disease.

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Last modified
  • 02/20/2025
Type of Material
Authors
    Bruce Crosson, Emory UniversityKeith McGregor, Emory UniversityJoe R. Nocera, Emory UniversityJonathan H. Drucker, Emory UniversityStella M. Tran, Atlanta VA Medical CenterAndrew Butler, Emory University
Language
  • English
Date
  • 2015
Publisher
  • Frontiers
Publication Version
Copyright Statement
  • © 2015 Crosson, McGregor, Nocera, Drucker, Tran and Butler.
License
Final Published Version (URL)
Title of Journal or Parent Work
ISSN
  • 1662-5161
Volume
  • 9
Start Page
  • 307
End Page
  • 307
Grant/Funding Information
  • This work was supported by the following grants from the US Department of Veterans Affairs Rehabilitation Research and Development Service: Grant # B6364L, Senior Research Career Scientist Award to BC; Grant # B0994P, Right Frontal Activity in Older Adults: Does It Help or Hurt Word Retrieval? to BC; Grant # E0596W, Effects of Exercise Intervention on Aging Related Motor Decline to KMM; Grant # 8034W, Aeorbic Exercise and Cognitive Training in Older Adults to JRN; a Georgia State Language and Literacy fellowship to SMT; Grant # B7676P, Brain Activations in Humans to AJB.
Abstract
  • The effects of aging on rehabilitation of aging-related diseases are rarely a design consideration in rehabilitation research. In this brief review we present strong coincidental evidence from these two fields suggesting that deficits in aging-related disease or injury are compounded by the interaction between aging-related brain changes and disease-related brain changes. Specifically, we hypothesize that some aphasia, motor, and neglect treatments using repetitive transcranial magnetic stimulation (rTMS) or transcranial direct current stimulation (tDCS) in stroke patients may address the aging side of this interaction. The importance of testing this hypothesis and addressing the larger aging by aging-related disease interaction is discussed. Underlying mechanisms in aging that most likely are relevant to rehabilitation of aging-related diseases also are covered.
Author Notes
Keywords
Research Categories
  • Psychology, General
  • Biology, Neuroscience

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