Metacognitive function and fragmentation in schizophrenia: Relationship to cognition, self-experience and developing treatments

• Type of Material: Article
• Authors: Paul H. Lysaker, Indiana University School of Medicine; Kyle S. Minor, Indiana University-Purdue University at Indianapolis; John Lysaker, Emory University; Ilanit Hasson-Ohayon, Bar Ilan University; Kelsey Bonfils, VA Pittsburgh Healthcare System; Jesse Hochheiser, University of Nebraska-Lincoln; Jenifer L. Vohs, Indiana University School of Medicine
• Language: English
• Date: 2020-03-01
• Publisher: Elsevier
• Publication Version: Final Published Version
• Copyright Statement: © 2019 Published by Elsevier Inc.
• License: Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.1016/j.scog.2019.100142
• Title of Journal or Parent Work: Schizophrenia Research: Cognition
• Volume: 19
• Keywords: neurocognition; rehabilitation; schizophrenia; insight; metacognition; recovery
• Research Categories: Psychology, General

Abstract

Bleuler suggested that fragmentation of thought, emotion and volition were the unifying feature of the disorders he termed schizophrenia. In this paper we review research seeking to measure some of the aspects of fragmentation related to the experience of the self and others described by Bleuler. We focus on work which uses the concept of metacognition to characterize and quantify alterations or decrements in the processes by which fragments or pieces of information are integrated into a coherent sense of self and others. We describe the rationale and support for one method for quantifying metacognition and its potential to study the fragmentation of a person's sense of themselves, others and the relative place of themselves and others in the larger human community. We summarize research using that method which suggests that deficits in metacognition commonly occur in schizophrenia and are related to basic neurobiological indices of brain functioning. We also present findings indicating that the capacity for metacognition in schizophrenia is positively related to a broad range of aspects of psychological and social functioning when measured concurrently and prospectively. Finally, we discuss the evolution and study of one therapy that targets metacognitive capacity, Metacognitive Reflection and Insight Therapy (MERIT) and its potential to treat fragmentation and promote recovery.