Neural oscillations underlying selective attention follow sexually divergent developmental trajectories during adolescence

• Type of Material: Article
• Authors: Brittany K Taylor, Boys Town National Research Hospital; Jacob A Eastman, Boys Town National Research Hospital; Michaela R Frenzel, Boys Town National Research Hospital; Christine M Embury, Boys Town National Research Hospital; Yu-Ping Wang, Tulane University; Vince Calhoun, Emory University; Julia M Stephen, Mind Research Network, Albuquerque; Tony W Wilson, Boys Town National Research Hospital
• Language: English
• Date: 2021-05-10
• Publisher: ELSEVIER SCI LTD
• Publication Version: Final Published Version
• Copyright Statement: © 2021 The Authors
• License: Creative Commons Attribution 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.1016/j.dcn.2021.100961
• Title of Journal or Parent Work: DEVELOPMENTAL COGNITIVE NEUROSCIENCE
• Volume: 49
• Start Page: 100961
• End Page: 100961
• Grant/Funding Information: This work was supported by the National Science Foundation (#1539067); and the National Institutes of Health (R01-MH121101, R01-MH116782, R01-MH118013, P20-GM103472, R01-EB020407). The funders had no role in the study design, collection, analysis, or interpretation of data, nor did they influence writing the report or the decision to submit this work for publication.
• Keywords: THETA; Psychology; EEG; Social Sciences; BRAIN ACTIVITY; Oscillations; Sex effects; MEG; Life Sciences & Biomedicine; RESPONSE COMPETITION; Science & Technology; DYNAMICS; Flanker effect; FRONTAL-LOBE; MECHANISMS; Neurosciences; Neurosciences & Neurology; Psychology, Developmental; Development; ALPHA; Magnetoencephalography (MEG); COGNITIVE CONTROL
• Research Categories: Psychology, General; Engineering, Biomedical

Abstract

Selective attention processes are critical to everyday functioning and are known to develop through at least young adulthood. Although numerous investigations have studied the maturation of attention systems in the brain, these studies have largely focused on the spatial configuration of these systems; there is a paucity of research on the neural oscillatory dynamics serving selective attention, particularly among youth. Herein, we examined the developmental trajectory of neural oscillatory activity serving selective attention in 53 typically developing youth age 9-to-16 years-old. Participants completed the classic arrow-based flanker task during magnetoencephalography, and the resulting data were imaged in the time-frequency domain. Flanker interference significantly modulated theta and alpha/beta oscillations within prefrontal, mid-cingulate, cuneus, and occipital regions. Interference-related neural activity also increased with age in the temporoparietal junction and the rostral anterior cingulate. Sex-specific effects indicated that females had greater theta interference activity in the anterior insula, whereas males showed differential effects in theta and alpha/beta oscillations across frontoparietal regions. Finally, males showed age-related changes in alpha/beta interference in the cuneus and middle frontal gyrus, which predicted improved behavioral performance. Taken together, these data suggest sexually-divergent developmental trajectories underlying selective attention in youth.