Publication

Editorial: Neuromodulatory Control of Spinal Function in Health and Disease

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Last modified
  • 05/15/2025
Type of Material
Authors
    Brian R. Noga, University of MiamiShawn Hochman, Emory UniversityHans Hultborn, University of Copenhagen
Language
  • English
Date
  • 2020-01-22
Publisher
  • Frontiers Media S.A.
Publication Version
Copyright Statement
  • © 2020 Noga, Hochman and Hultborn.
License
Final Published Version (URL)
Title of Journal or Parent Work
Volume
  • 13
Start Page
  • 84
End Page
  • 84
Grant/Funding Information
  • None declared
Abstract
  • The classical ionotropic transmitters glutamate/ACh (acetylcholine) and glycine/GABA (gamma-amino butyric acid) are, respectively, responsible for the primary excitatory and inhibitory synaptic actions within spinal cord anatomical circuits, be they simple reflexes as the monosynaptic stretch reflex (and its reciprocal inhibition of antagonists), or more distributed and integrated networks along autonomic, sensory, and motor systems. The selection and complex spatiotemporal recruitment of intrinsic spinal circuits (e.g., locomotion) are profoundly sculpted by neuromodulation acting both at pre- and post-synaptic levels.
Author Notes
Keywords
Research Categories
  • Biology, Neuroscience
  • Engineering, Biomedical
  • Biology, Physiology

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