Advances in Wireless, Batteryless, Implantable Electronics for Real-Time, Continuous Physiological Monitoring

• Type of Material: Article
• Authors: Hyeonseok Kim, Georgia Institute of Technology; Bruno Rigo, Georgia Institute of Technology; Gabriella Wong, Georgia Institute of Technology; Yoon Jae Lee, Georgia Institute of Technology; Woong-Hong Yeo, Emory University
• Language: English
• Date: 2023-12-15
• Publisher: Springer
• Publication Version: Final Published Version
• Copyright Statement: © The Author(s) 2023
• License: Creative Commons Attribution 4.0 International
• Final Published Version (URL): https://doi.org/10.1007/s40820-023-01272-6
• Title of Journal or Parent Work: Nano-Micro Letters
• Volume: 16
• Start Page: 52
• Grant/Funding Information: We acknowledge the support of the NSF CCSS-2152638 and the IEN Center Grant from the Institute for Electronics and Nanotechnology at Georgia Tech.
• Keywords: Wireless electronics; Physiological signal monitoring; Batteryless devices; Implantable electronics; Biomedical systems
• Research Categories: Engineering, Biomedical; Engineering, Materials Science

Abstract

This review summarizes recent progress in developing wireless, batteryless, fully implantable biomedical devices for real-time continuous physiological signal monitoring, focusing on advancing human health care. Design considerations, such as biological constraints, energy sourcing, and wireless communication, are discussed in achieving the desired performance of the devices and enhanced interface with human tissues. In addition, we review the recent achievements in materials used for developing implantable systems, emphasizing their importance in achieving multi-functionalities, biocompatibility, and hemocompatibility. The wireless, batteryless devices offer minimally invasive device insertion to the body, enabling portable health monitoring and advanced disease diagnosis. Lastly, we summarize the most recent practical applications of advanced implantable devices for human health care, highlighting their potential for immediate commercialization and clinical uses.