Gastric Ulcer as Presentation of HIV-Associated Kaposi Sarcoma and Resolution With HAART Therapy

• Type of Material: Article
• Authors: Rama Nassri, Alfaisal University College of Medicine; Abdullah Muftah, USF Morsani College of Medicine, Tampa; Mayssan Muftah, Emory University; Ammar Nassri, University of Florida at Jacksonville; Ahmad Alkhasawneh, University of Florida at Jacksonville
• Language: English
• Date: 2019-10-28
• Publisher: American College of Gastroenterology
• Publication Version: Final Published Version
• Copyright Statement: © 2019 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology.
• License: Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.14309/crj.0000000000000262
• Title of Journal or Parent Work: ACG Case Reports Journal
• Volume: 6
• Issue: 10
• Keywords: Gastric Ulcer; HAART Therapy
• Research Categories: Health Sciences, Pathology; Health Sciences, Medicine and Surgery

Abstract

Kaposi sarcoma (KS) is a neoplasm of endothelium-derived cells that are associated with human herpesvirus 8 infection. In the setting of HIV, extensive disease typically necessitates highly active antiretroviral therapy in conjunction with chemotherapy. We report a patient who presented with gastrointestinal symptoms and was found to have KS presenting only as cratered gastric ulcers. The patient declined chemotherapy and was treated with highly active antiretroviral therapy alone and had complete resolution of KS on endoscopy and imaging up to 3 years later.