Diverse Applications of Nanomedicine.

• Type of Material: Article
• Authors: Beatriz Pelaz, Philipps Universität Marburg; Christoph Alexiou, University Hospital Erlangen; Ramon A. Alvarez-Puebla, Universitat Rovira I Virgili; Frauke Alves, University Medical Center Göttingen; Anne M. Andrews, California NanoSystems Institute; Sumaira Ashraf, Philipps Universität Marburg; Lajos P. Balogh, AA Nanomedicine & Nanotechnology Consultants, North Andover, Massachusetts 01845, United States.; Laura Ballerini, International School for Advanced Studies (SISSA/ISAS); Alessandra Bestetti, University of Melbourne; Cornelia Brendel, Philipps Universität Marburg; Susanna Bosi, University of Trieste; Monica Carril, Basque Foundation for Science; Warren C. W. Chan, University of Toronto; Chunying Chen, National Center for Nanoscience and Technology of China; Xiaodong Chen, Nanyang Technological University; Xiaoyuan Chen, National Institutes of Health; Zhen Cheng, Stanford University; Daxiang Cui, Shanghai Jiao Tong University; Jianzhong Du, Tongji University; Christian Dullin, University Medical Center Göttingen; Alberto Escudero, Philipps Universität Marburg; Neus Feliu, Karolinska Institutet; Mingyuan Gao, Chinese Academy of Sciences; Michael George, Nanion; Yury Gogotsi, Drexel University; Arnold Grünweller, Philipps Universität Marburg; Zhongwei Gu, Sichuan University; Naomi J. Halas, Rice University; Nobert Hampp, Philipps Universität Marburg; Roland K. Hartmann, Philipps Universität Marburg; Mark C. Hersam, Northwestern University; Patrick Hunziker, University Hospital; Ji Jian, Zhejiang University; Xingyu Jiang, National Center for Nanoscience and Technology of China; Phillip Jungebluth, Universitätsklinikum Heidelberg; Pranav Kadhiresan, University of Toronto; Kazunori Kataoka, The University of Tokyo; Ali Khademhosseini, Havard University; Jindřich Kopeček, University of Utah; Nicholas A. Kotov, University of Michigan, Ann Arbor; Harald F. Krug, Federal Institute for Materials Science and Technology; Dong Soo Lee, Seoul National University; Claus-Michael Lehr, Saarland University; Kam W. Leong, Columbia University; Xing-Jie Liang, National Center for Nanoscience and Technology of China; Mei Ling Lim, Karolinska Institutet; Luis M. Liz-Marzán, Basque Foundation for Science; Xiaowei Ma, Chinese Academy of Sciences (CAS); Paolo Macchiarini, Kazan Federal University; Huan Meng, California NanoSystems Institute; Helmuth Möhwald, Max-Planck Institute of Colloids and Interfaces; Paul Mulvaney, University of Melbourne; Andre E. Nel, California NanoSystems Institute; Shuming Nie, Emory University; Peter Nordlander, Rice University; Teruo Okano, Tokyo Women's Medical University; Jose Oliveira, SMALL; Tai Hyun Park, Advanced Institutes of Convergence Technology; Reginald M. Penner, University of California Irvine; Maurizio Prato, University of Trieste; Victor Puntes, ICREA; Vincent M. Rotello, University of Massachusetts Amherst; Amila Samarakoon, University of Toronto; Raymond E. Schaak, The Pennsylvania State University; Youqing Shen, Zhejiang University; Sebastian Sjöqvist, Karolinska Institutet; Andre G. Skirtach, Max-Planck Institute of Colloids and Interfaces; Mahmoud G. Soliman, Philipps Universität Marburg; Molly M. Stevens, Imperial College London; Hsing-Wen Sung, National Tsing Hua University; Ben Zhong Tang, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction; Rainer Tietze, University Hospital Erlangen; Buddhisha N. Udugama, University of Toronto; J. Scott VanEpps, University of Michigan Ann Arbor; Tanja Weil, Universität Ulm; Paul S. Weiss, California NanoSystems Institute; Itamar Willner, The Hebrew University of Jerusalem; Yuzhou Wu, Max-Planck-Institute for Polymer Research, 55128 Mainz, Germany.; Lily Yang, SMALL; Zhao Yue, Philipps Universität Marburg; Qian Zhang, Philipps Universität Marburg; Qiang Zhang, Peking University; Xian-En Zhang, Chinese Academy of Sciences; Yuliang Zhao, National Center for Nanoscience and Technology of China; Xin Zhou, Chinese Academy of Sciences; Wolfgang J. Parak, Philipps Universität Marburg
• Language: English
• Date: 2017-03-14
• Publisher: American Chemical Society
• Publication Version: Author Accepted Manuscript (After Peer Review)
• Copyright Statement: © 2017 American Chemical Society
• Final Published Version (URL): http://dx.doi.org/10.1021/acsnano.6b06040
• Title of Journal or Parent Work: ACS Nano
• ISSN: 1936-0851
• Volume: 11
• Issue: 3
• Start Page: 2313
• End Page: 2381
• Grant/Funding Information: See publication for full funding statement.
• Keywords: nanomedicine; nanoscale
• Research Categories: Chemistry, Pharmaceutical; Biology, Molecular

Abstract

The design and use of materials in the nanoscale size range for addressing medical and health-related issues continues to receive increasing interest. Research in nanomedicine spans a multitude of areas, including drug delivery, vaccine development, antibacterial, diagnosis and imaging tools, wearable devices, implants, high-throughput screening platforms, etc. using biological, nonbiological, biomimetic, or hybrid materials. Many of these developments are starting to be translated into viable clinical products. Here, we provide an overview of recent developments in nanomedicine and highlight the current challenges and upcoming opportunities for the field and translation to the clinic.