Publication

Neuro-Modulating Effects of Honokiol: A Review

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Last modified
  • 02/20/2025
Type of Material
Authors
    Anna Woodbury, Emory UniversityShan Ping Yu, Emory UniversityLing Wei, Emory UniversityPaul Garcia, Emory University
Language
  • English
Date
  • 2013
Publisher
  • Frontiers
Publication Version
Copyright Statement
  • © 2013 Woodbury, Yu, Wei and Garcia.
Final Published Version (URL)
Title of Journal or Parent Work
ISSN
  • 1664-2295
Volume
  • 4
Issue
  • 130
Grant/Funding Information
  • This research was supported in part by the Foundation for Anesthesia Education and Research (FAER), the James S. McDonnell Foundation and a VA Career Development Award.
Abstract
  • Honokiol is a poly-phenolic compound that exerts neuroprotective properties through a variety of mechanisms. It has therapeutic potential in anxiety, pain, cerebrovascular injury, epilepsy, and cognitive disorders including Alzheimer’s disease. It has been traditionally used in medical practices throughout much of Southeast Asia, but has now become more widely studied due to its pleiotropic effects. Most current research regarding this compound has focused on its chemotherapeutic properties. However, it has the potential to be an effective neuroprotective agent as well. This review summarizes what is currently known regarding the mechanisms involved in the neuroprotective and anesthetic effects of this compound and identifies potential areas for further research.
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Research Categories
  • Health Sciences, General

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