Opportunities for Examining Child Health Impacts of Early-Life Nutrition in the ECHO Program: Maternal and Child Dietary Intake Data from Pregnancy to Adolescence

• Type of Material: Article
• Authors: Megan G. Bragg, Drexel University; Matt Westlake, RTI International; Akram N. Alshawabkeh, Northeastern University; Traci A. Bekelman, University of Colorado; Carlos A. Camargo, Jr., Harvard Medical School; Diane J. Catellier, RTI International; Sarah S. Comstock, Michigan State University; Dana Dabelea, University of Colorado; Anne Lang Dunlop, Emory University; Monique M. Hedderson, Kaiser Permanente Northern California Division of Research; Christine W. Hockett, University of South Dakota; Margaret R. Karagas, Geisel School of Medicine at Dartmouth; Kate Keenan, University of Chicago; Nichole R. Kelly, University of Oregon; Jean M. Kerver, Michigan State University; Debra MacKenzie, University of New Mexico; Somdat Mahabir, National Institutes of Health; Luis E. Maldonado, University of Southern California; Lacey A. McCormack, University of South Dakota; Melissa M. Melough, University of Delaware; Noel T. Mueller, Johns Hopkins University; Morgan E. Nelson, RTI International; Thomas G. O'Connor, University of Rochester; Emily Oken, Harvard Medical School; T. Michael O'Shea, University of North Carolina; Karen M. Switkowski, Harvard Medical School; Katherine A. Sauder, University of Colorado; Rosalind J. Wright, Icahn School of Medicine at Mount Sinai; Robert O. Wright, Icahn School of Medicine at Mount Sinai; Xueying Zhang, Icahn School of Medicine at Mount Sinai; Yeyi Zhu, Kaiser Permanente Northern California Division of Research; Kristen Lyall, Drexel University
• Language: English
• Date: 2023-10-23
• Publisher: Elsevier
• Publication Version: Final Published Version
• Copyright Statement: © 2023 The Author(s)
• License: Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International
• Final Published Version (URL): https://doi.org/10.1016/j.cdnut.2023.102019
• Title of Journal or Parent Work: Current Developments in Nutrition
• Volume: 7
• Issue: 11
• Start Page: 102019
• Grant/Funding Information: Research reported in this publication was supported by the Environmental influences on Child Health Outcomes (ECHO) program, Office of the Director, National Institutes of Health, under Award Numbers U2COD023375 (Coordinating Center), U24OD023382 (Data Analysis Center), U24OD023319 with co-funding from the Office of Behavioral and Social Science Research (PRO Core), U24ES026539 (HHEAR O’Brien), U2CES026533 (HHEAR Peterson), U2CES026542 (HHEAR Parsons, Kannan), UH3OD023251 (Alshawabkeh), UH3OD023320 (Aschner), UH3OD023332 (Trasande), UH3OD023253 (Camargo), UH3OD023248 (Dabelea), UH3OD023313 (Koinis Mitchell), UH3OD023328 (Duarte), UH3OD023318 (Dunlop), UH3OD023279 (Elliott), UH3OD023289 (Ferrara), UH3OD023282 (Gern), UG3/UH3OD023287 (Breton/Maldonado), UH3OD023365 (Hertz-Picciotto), UH3OD023244 (Hipwell), UH3OD023275 (Karagas), UH3OD023271 (Karr), UH3OD023347 (Lester), UH3OD023389 (Leve), UH3OD023344 (MacKenzie), UH3OD023268 (Weiss), UH3OD023288 (McEvoy), UH3OD023342 (Lyall), UH3OD023349 (O’Connor), UH3OD023286 (Oken), UH3OD023348 (O’Shea), UH3OD023285 (Kerver), UH3OD023290 (Herbstman), UH3OD023272 (Schantz), UH3OD023249 (Stanford), UH3OD023305 (Trasande), and UH3OD023337 (Wright).
• Keywords: child nutrition; child health; diet assessment; nutrition research; nutrient biomarkers; pregnancy nutrition
• Research Categories: Health Sciences, Nutrition; Health Sciences, Human Development

Abstract

Background Longitudinal measures of diet spanning pregnancy through adolescence are needed from a large, diverse sample to advance research on the effect of early-life nutrition on child health. The Environmental influences on Child Health Outcomes (ECHO) Program, which includes 69 cohorts, >33,000 pregnancies, and >31,000 children in its first 7-y cycle, provides such data, now publicly available. Objectives This study aimed to describe dietary intake data available in the ECHO Program as of 31 August, 2022 (end of year 6 of Cycle 1) from pregnancy through adolescence, including estimated sample sizes, and to highlight the potential for future analyses of nutrition and child health. Methods We identified and categorized ECHO Program dietary intake data, by assessment method, participant (pregnant person or child), and life stage of data collection. We calculated the number of maternal-child dyads with dietary data and the number of participants with repeated measures. We identified diet-related variables derived from raw dietary intake data and nutrient biomarkers measured from biospecimens. Results Overall, 66 cohorts (26,941 pregnancies, 27,103 children, including 22,712 dyads) across 34 US states/territories provided dietary intake data. Dietary intake assessments included 24-h recalls (1548 pregnancies and 1457 children), food frequency questionnaires (4902 and 4117), dietary screeners (8816 and 23,626), and dietary supplement use questionnaires (24,798 and 26,513). Repeated measures were available for ∼70%, ∼30%, and ∼15% of participants with 24-h recalls, food frequency questionnaires, and dietary screeners, respectively. The available diet-related variables describe nutrient and food intake, diet patterns, and breastfeeding practices. Overall, 17% of participants with dietary intake data had measured nutrient biomarkers. Conclusions ECHO cohorts have collected longitudinal dietary intake data spanning pregnancy through adolescence from a geographically, socioeconomically, and ethnically diverse US sample. As data collection continues in Cycle 2, these data present an opportunity to advance the field of nutrition and child health.