The Burden of Living With Cutaneous Lupus Erythematosus

• Type of Material: Article
• Authors: Cristina Drenkard, Emory University; Kamil E Barbour, Centers for Disease Control and Prevention, Atlanta; Kurt J Greenlund, Centers for Disease Control and Prevention, Atlanta; Sung Lim, Emory University
• Language: English
• Date: 2022-08-08
• Publisher: FRONTIERS MEDIA SA
• Publication Version: Final Published Version
• Copyright Statement: © 2022 Drenkard, Barbour, Greenlund and Lim.
• License: Creative Commons Attribution 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.3389/fmed.2022.897987
• Title of Journal or Parent Work: FRONTIERS IN MEDICINE
• Volume: 9
• Start Page: 897987
• End Page: 897987
• Grant/Funding Information: SL and CD are supported by the NIH (R01AR065493-01; R01MD010455-01; R01AR070898-01) and the CDC (U01DP005119).; This publication was supported by the Centers for Disease Control and Prevention of the U.S. Department of Health and Human Services (HHS) under Grant numbers U01 DP19003, U01 DP005119 and by cooperative agreement CDC-RFA-DP08-806 as part of a financial assistance award totaling $6,406,636 with 100% funded by CDC/HHS.
• Keywords: psychosocial impact; RISK-FACTORS; PREVALENCE; STRESS; quality of life; Medicine, General & Internal; CLINICAL-MANIFESTATIONS; PROGRESSION; DISEASE; disease burden; racial minorities; WOMEN; POPULATION; Science & Technology; ASSOCIATION; QUALITY-OF-LIFE; cutaneous lupus erythematosus (CLE); Life Sciences & Biomedicine; General & Internal Medicine
• Research Categories: Public Administration; Health Sciences, Epidemiology

Abstract

Cutaneous lupus erythematosus (CLE) is a group of heterogeneous autoimmune disorders primarily affecting the skin. Patients with these conditions are mostly young women when they become sick and often suffer from recurrent skin symptoms or longstanding changes in their physical appearance. CLE disorders lead to different levels of morbidity and can impact profoundly patients' quality of life, particularly in the psychological and social health domains. This review provides a summary of recent research investigating the psychosocial burden of living with CLE and the intersect amongst the disease characteristics, patient factors, and social determinants of health. Furthermore, this review provides insight into patient care and research needs that remain unmet to improve the quality of life of patients living with CLE.