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Alternate Warm and Cold Therapy (AWCT) on Uricemia, Sleep, Pain, Functional Ability, and Quality of Life (USPFQoL) in Patients with Gout: A Path Forward

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Last modified
  • 05/22/2025
Type of Material
Authors
    Premalatha Paulsamy, Mahalah Branch Girls King Khalid UnivKrishnaraju Venkatesan, King Khalid UniversityShadia Hamoud Alshahrani, King Khalid UniversityFazil Ahmad, Imam Ab-dulrahman Bin Faisal UniversityMohamed El-Sherbiny, Almaarefa UniversityVani Manoharan, Emory University HospitalKalaiselvi Periannan, Oxford School of Nursing & MidwiferyRasha Elsayed Ahmed, College of Nursing Tanta UniversityKousalya Prabahar, University of TabukDawit M Teressa, Addis Ababa Science and Technology University
Language
  • English
Date
  • 2022-03-09
Publisher
  • HINDAWI LTD
Publication Version
Copyright Statement
  • © 2022 Premalatha Paulsamy et al.
License
Final Published Version (URL)
Title of Journal or Parent Work
Volume
  • 2022
Start Page
  • 5471575
End Page
  • 5471575
Abstract
  • Objective. To understand the impact of alternate warm and cold therapy (AWCT) on uricemia, sleep, pain, functional ability, and quality of life in gout patients. Methods. A quasiexperimental, nonequivalent control group, pre and posttest design was adopted among 120 gout patients. The data were collected on demographics, comorbidities, pain level, joint swelling/joint tenderness, patient global assessment of response to treatment (PGART), health-related quality of life (HRQoL) with SF-36, sleep quality by Pittsburgh Sleep Quality Index (PSQI), and serum uric acid and assessed. Descriptive and inferential statistics were used to analyze the data. Results. Patients had mean age of 58 and 61 years, mean number of comorbidities was 1.8 and 1.4, as well as presence of arthritic comorbidities except gout was 1.1 and 0.8 among study and control group participants, respectively. Pain (p<0.001), PGART (p=-0.01), HRQoL, sleep quality, and level of SUA (mg/dl) improved significantly (p<0.01) among the study group over study periods. It affirms that the AWCT is effective in reducing pain, functional disability, and SUA, as well as improving the sleep quality and HRQoL of the gout patients. There was a reduced incidence of gout flares (p<0.001), and taking additional medicines for pain (p<0.01) was statistically significant among study participants. Except social functioning, other domains of health were significantly (p<0.05) affected by the comorbidities like hypertension, diabetes, heart disease, renal disease, and asthma/chronic obstructive pulmonary disease. Conclusions. Gout is independently associated with higher medical and arthritic comorbidity, and AWCT can be better and cost-effective alternative therapy for gout patients. In addition, it may lead to improved cardiac function, hypertension, and renal insufficiency.
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Research Categories
  • Health Sciences, Pharmacology
  • Engineering, Chemical
  • Health Sciences, Nursing

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