Eliminating perinatal HIV in the United States: mission possible?

• Type of Material: Article
• Authors: Devasena Gnanashanmugam, National Institute of Allergy and Infectious Diseases; Natella Rakhmanina, Elizabeth Glaser Pediatric AIDS Foundation; Keith Crawford, National Institute of Allergy and Infectious Diseases; Steven Nesheim, Emory University; Theodore Ruel, University of California San Francisco; Guthrie S. Birkhead, University at Albany; Rana Chakraborty, Emory University; Robert Lawrence, University of Florida; Patrick Jean-Philippe, National Institute of Allergy and Infectious Diseases; Lakshmi Jayashankar, National Institute of Allergy and Infectious Diseases; Ashley Hoover, Louisiana State Department of Health; Anne Statton, Pediatric AIDS Chicago Prevention Initiative; Patricia D'Souza, National Institute of Allergy and Infectious Diseases; Joseph Fitzgibbon, National Institute of Allergy and Infectious Diseases; Rohan Hazra, Eunice Kennedy Shriver National Institute of Child Health and Human Development; Barbara Warren, New York State Department of Health; Somer Smith, Emory University; Elaine J. Abrams, Columbia University
• Language: English
• Date: 2019-03-01
• Publisher: Lippincott Williams & Wilkins
• Publication Version: Author Accepted Manuscript (After Peer Review)
• Copyright Statement: © 2019 Wolters Kluwer Health, Inc. All rights reserved.
• License: Creative Commons Attribution-NonCommercial 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.1097/QAD.0000000000002080
• Title of Journal or Parent Work: AIDS
• Volume: 33
• Issue: 3
• Start Page: 377
• End Page: 385
• Grant/Funding Information: No funding was secured for this study.
• Keywords: Prevention; United States; Infection; perinatal; Life Sciences & Biomedicine; Virology; To child transmission; Missed opportunities; Science & Technology; Immunology; HIV transmission; Combination antiretroviral; Infectious Diseases
• Research Categories: Health Sciences, Public Health; Health Sciences, Immunology; Health Sciences, Human Development; Biology, Virology

Abstract

In 2015, only 53 infants born in the United States acquired HIV - the lowest recorded number of perinatal HIV infections. Recognizing this significant achievement, we must acknowledge that the United States has not yet reached the goal of eliminating perinatal HIV transmission. This analysis describes different approaches to perinatal HIV preventive services among five states and the District of Columbia as case studies. Continuous focus on improving identification, surveillance and prevention of HIV infection in pregnant women and their infants is necessary to reach the goal of eliminating perinatal HIV transmission in the United States.