Assessing the Reliability of the OMERACT Juvenile Idiopathic Arthritis Magnetic Resonance Scoring System for Temporomandibular Joints (JAMRIS-TMJ)

• Type of Material: Article
• Authors: Mirkamal Tolend, University of Toronto; Andrea S Doria, University of Toronto; Arthur B Meyers, Children’s Hospital Medical Center; Tore A Larheim, University of Oslo; Shelly Abramowicz, Emory University; Julien Aguet, The Hospital for Sick Children; Simone Appenzeller, University of Campinas; Linda Z Arvidsson, University of Oslo; Lauren W Averill, Nemours Children’s Health System; Brian M Feldman, University of Toronto; Saurabh Guleria, Austin Radiological Association; Emilio J Inarejos Clemente, Hospital Sant Joan de Deu; Jacob L Jaremko, University of Alberta; Thitiporn Junhasavasdikul, Mahidol University; Thekla von Kalle, Olgahosp Klinikum Stuttgart; Eva Kirkhus, Oslo University Hospital; Bernd Koos, University Hospital Tübingen; Elka Miller, University of Ottawa; Rahim Moineddin, University of Toronto; Jyoti Panwar, Christian Medical College and Hospital; Zachary S Peacock, Massachusetts General Hospital; Cory M Resnick, Boston Children’s Hospital; Marion A van Rossum, Amsterdam University Medical Center; Jennifer Stimec, The Hospital for Sick Children; George Tomlinson, University Health Network; Nikolay Tzaribachev, Pediatric Rheumatology Research Institute; Christian J Kellenberger, University Children’s Hospital Zürich
• Language: English
• Date: 2021-09-01
• Publisher: MDPI
• Publication Version: Final Published Version
• Copyright Statement: © 2021 by the authors.
• License: Creative Commons Attribution 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.3390/jcm10184047
• Title of Journal or Parent Work: JOURNAL OF CLINICAL MEDICINE
• Volume: 10
• Issue: 18
• Grant/Funding Information: Mirkamal Tolend was supported by research scholarship awards from Queen Elizabeth II/Edward Dunlop foundation, Peterborough K. M. Hunter Charitable Foundation, The Hospital for Sick Children ResTraComp, Ontario Graduate Scholarship and Mergelas Family foundation for this study.
• Keywords: SYNOVIAL ENHANCEMENT; CHILDREN; outcome measure; Life Sciences & Biomedicine; magnetic resonance imaging; reliability; generalizability theory; juvenile idiopathic arthritis; Medicine, General & Internal; General & Internal Medicine; temporomandibular joints; PREVALENCE; Science & Technology; INVOLVEMENT
• Research Categories: Health Sciences, Radiology; Health Sciences, Medicine and Surgery

Abstract

Contrast-enhanced magnetic resonance imaging (MRI) remains the most comprehensive modality to assess juvenile idiopathic arthritis (JIA)-related inflammation and osteochondral damage in the temporomandibular joints (TMJ). This study tested the reliability of a new JIA MRI scoring system for TMJ (JAMRIS-TMJ) and the impact of variations in calibration and reader specialty. Thirty-one MRI exams of bilateral TMJs were scored independently using the JAMRIS-TMJ by 20 readers consisting of radiologists and non-radiologist clinicians in three reading groups, with or without a calibrating atlas and/or tutorial. The inter-reader reliability in the multidisciplinary cohort assessed by the generalizability coefficient was 0.61–0.67 for the inflammatory and 0.66–0.74 for the damage domain. The atlas and tutorial did not improve agreement within radiologists, but improved the agreement between radiologist and non-radiologist groups. Agreements between different calibration levels were 0.02 to 0.08 lower by the generalizability coefficient compared to agreement within calibration levels; agreement between specialty groups was 0.04 to 0.10 lower than within specialty groups. Averaging two radiologists raised the reliability above 0.8 for both domains. Therefore, the reliability of JAMRIS-TMJ was moderate-to-good depending on the presence of specialty and calibration differences. The atlas and tutorial are necessary to improve reliability when the reader cohort consists of multiple specialties.