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Evolving Applications, Technological Challenges and Future Opportunities in Neuromodulation: Proceedings of the Fifth Annual Deep Brain Stimulation Think Tank

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  • 03/14/2025
Type of Material
Authors
    Adolfo Ramirez-Zamora, University of FloridaJames J. Giordano, Georgetown UniversityAysegul Gunduz, University of FloridaPeter Brown, University of OxfordJustin C. Sanchez, Defense Advanced Research Projects AgencyKelly D. Foote, University of FloridaLeonardo Almeida, University of FloridaPhilip A. Starr, University of California San FranciscoHelen M. Bronte-Stewart, Stanford UniversityWei Hu, University of FloridaCameron McIntyre, Case Western Reserve UniversityWayne Goodman, Icahn School of Medicine at Mount SinaiDoe Kumsa, United States Food and Drug AdministrationWarren M. Grill, Duke UniversityHarrison C. Walker, University of Alabama BirminghamMatthew D. Johnson, University of MinnesotaJerrold L. Vitek, University of MinnesotaDavid Greene, NeuroPace, Inc.Daniel S. Rizzuto, University of PennsylvaniaDong Song, University of Southern CaliforniaTheodore W. Berger, University of Southern CaliforniaRobert E. Hampson, Wake Forest UniversitySam A. Deadwyler, Wake Forest UniversityLeigh R. Hochberg, Harvard UniversityNicholas D. Schiff, Weill Cornell MedicinePaul Stypulkowski, Medtronic NeuromodulationGreg Worrell, Mayo ClinicVineet Tiruvadi, Emory UniversityHelen S Mayberg, Emory UniversityJoohi Jimenez-Shahed, Baylor College of MedicinePranav Nanda, Colombia UniversitySameer A. Sheth, Colombia UniversityRobert Gross, Emory UniversityScott F. Lempka, University of MichiganLuming Li, Tsinghua UniversityWissam Deeb, University of FloridaMichael S. Okun, University of Florida
Language
  • English
Date
  • 2018-01-24
Publisher
  • Frontiers Media
Publication Version
Copyright Statement
  • © 2018 Ramirez-Zamora, Giordano, Gunduz, Brown, Sanchez, Foote, Almeida, Starr, Bronte-Stewart, Hu, McIntyre, Goodman, Kumsa, Grill, Walker, Johnson, Vitek, Greene, Rizzuto, Song, Berger, Hampson, Deadwyler, Hochberg, Schiff, Stypulkowski, Worrell, Tiruvadi, Mayberg, Jimenez-Shahed, Nanda, Sheth, Gross, Lempka, Li, Deeb and Okun.
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Final Published Version (URL)
Title of Journal or Parent Work
ISSN
  • 1662-4548
Volume
  • 11
Issue
  • JAN
Start Page
  • 734
End Page
  • 734
Grant/Funding Information
  • DS, TB, RH, and SD: this work was supported by DARPA RAM program (N66001-14-2-4032, N66001-14-C-4016).
  • JG is supported in part by funding from the European Union's Horizon 2020 Research and Innovation Program under grant agreement 720270: HBP SGA1, by the AEHS Foundation, and by federal funds UL1TR001409 from the National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, through the Clinical and Translational Science Awards Program (CTSA), a trademark of the Department of Health and Human Services, part of the Roadmap Initiative, “Re-Engineering the Clinical Research Enterprise.”
  • LL would like to acknowledge grant support NSFC No. 81527901, No. 61601258, and 2016YFC0105502 2016YFC0105900.
  • HW is supported by NIH grant UH3NS100553.
Abstract
  • The annual Deep Brain Stimulation (DBS) Think Tank provides a focal opportunity for a multidisciplinary ensemble of experts in the field of neuromodulation to discuss advancements and forthcoming opportunities and challenges in the field. The proceedings of the fifth Think Tank summarize progress in neuromodulation neurotechnology and techniques for the treatment of a range of neuropsychiatric conditions including Parkinson's disease, dystonia, essential tremor, Tourette syndrome, obsessive compulsive disorder, epilepsy and cognitive, and motor disorders. Each section of this overview of the meeting provides insight to the critical elements of discussion, current challenges, and identified future directions of scientific and technological development and application. The report addresses key issues in developing, and emphasizes major innovations that have occurred during the past year. Specifically, this year's meeting focused on technical developments in DBS, design considerations for DBS electrodes, improved sensors, neuronal signal processing, advancements in development and uses of responsive DBS (closed-loop systems), updates on National Institutes of Health and DARPA DBS programs of the BRAIN initiative, and neuroethical and policy issues arising in and from DBS research and applications in practice.
Author Notes
Keywords
Research Categories
  • Biology, Neuroscience
  • Engineering, Biomedical

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