The relationship between allergy and chronic rhinosinusitis.

• Type of Material: Article
• Authors: Sonya Marcus, Emory University; Lauren Roland, Emory University; John M DelGaudio, Emory University; Sarah K Wise, Emory University
• Language: English
• Date: 2019-02
• Publisher: Wiley Open Access
• Publication Version: Final Published Version
• Copyright Statement: © 2018 The Authors. Laryngoscope Investigative Otolaryngology published by Wiley Periodicals, Inc. on behalf of The Triological Society.
• License: Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.1002/lio2.236
• Title of Journal or Parent Work: Laryngoscope Investigative Otolaryngology
• ISSN: 2378-8038
• Volume: 4
• Issue: 1
• Start Page: 13
• End Page: 17
• Keywords: Allergy; chronic rhinosinusitis; nasal polyposis; atopy; sinusitis
• Research Categories: Health Sciences, Medicine and Surgery

Abstract

Objective: To summarize the current evidence regarding a relationship between chronic rhinosinusitis (CRS) and allergy. Methods: Literature review. Results: Despite frequent assumption of an association between CRS and allergy the relationship between these entities remains poorly defined. Certain CRS entities, however, have demonstrated a strong association with allergy-namely allergic fungal rhinosinusitis and central compartment atopic disease. Conclusion: Studies are heterogeneous and largely retrospective in design with inconclusive evidence for an association between CRS and allergy. Knowledge of CRS endotypes is important in order to understand which entities may or may not be associated with allergy. Level of Evidence: 5.