Evolutionary consequences of feedbacks between within-host competition and disease control

• Type of Material: Article
• Authors: Megan A Greischar, University of Toronto; Helen K Alexander, University of Oxford; Farrah Bashey, Indiana University Bloomington; Ana I Bento, University of Georgia; Amrita Bhattacharya, Indiana University Bloomington; Mary Bushman, Emory University; Lauren M Childs, Virginia Polytechnic Institute and State University; David R Daversa, University of Liverpool; Troy Day, Queen’s University; Christina L Faust, College of Medical, Veterinary & Life Sciences; Molly E Gallagher, Emory University; Sylvain Gandon, Université de Montpellier; Caroline K Glidden, Oregon State University; Fletcher W Halliday, Universität Zürich; Kathryn A Hanley, New Mexico State University; Tsukushi Kamiya, University of Toronto; Andrew F Read, Huck Institutes of the Life Sciences; Philipp Schwabl, College of Medical, Veterinary & Life Sciences; Amy R Sweeny, University of Oxford; Ann T Tate, Vanderbilt University; Robin N Thompson, University of Oxford; Nina Wale, University of Michigan, Ann Arbor; Helen J Wearing, The University of New Mexico; Pamela J Yeh, University of California, Los Angeles; Nicole Mideo, University of Toronto
• Language: English
• Date: 2020-03-03
• Publisher: Oxford University Press
• Publication Version: Final Published Version
• Copyright Statement: © The Author(s) 2020. Published by Oxford University Press on behalf of the Foundation for Evolution, Medicine, and Public Health.
• License: Creative Commons Attribution 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.1093/emph/eoaa004
• Title of Journal or Parent Work: Evolution, Medicine and Public Health
• Volume: 2020
• Issue: 1
• Start Page: 30
• End Page: 34
• Grant/Funding Information: The workshop was organized by Megan A. Greischar and Nicole Mideo, and funded by the National Science Foundation's Infectious Disease Evolution across Scales (IDEAS) Research Coordination Network, hosted at Princeton University
• Keywords: Evolution; Disease control; Parasites; HIV infections; anemia
• Research Categories: Biology, General; Health Sciences, Epidemiology; Health Sciences, Public Health

Abstract

Lay Summary: Competition often occurs among diverse parasites within a single host, but control efforts could change its strength. We examined how the interplay between competition and control could shape the evolution of parasite traits like drug resistance and disease severity.