Do reminder emails and past due notifications improve patient completion and institutional data submission for patient-reported outcome measures?

• Type of Material: Article
• Authors: Stephanie L Pugh, American College of Radiology; Joseph P Rodgers, American College of Radiology; Jennifer Moughan, American College of Radiology; Roseann Bonanni, American College of Radiology; Jaskaran Boparai, American College of Radiology; Ronald C Chen, University of Kansas; James J Dignam, University of Chicago; Deborah Bruner, Emory University
• Language: English
• Date: 2020-09-07
• Publisher: SPRINGER
• Publication Version: Author Accepted Manuscript (After Peer Review)
• Copyright Statement: © 2020, Springer Nature Switzerland AG
• License: Creative Commons Attribution-NonCommercial 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.1007/s11136-020-02613-3
• Title of Journal or Parent Work: QUALITY OF LIFE RESEARCH
• Volume: 30
• Issue: 1
• Start Page: 81
• End Page: 89
• Grant/Funding Information: This project was supported by grants U10CA180868 (NRG Oncology Operations), U10CA180822 (NRG Oncology SDMC), UG1CA189867 (NCORP), CURE from the National Cancer Institute (NCI). The Department specifically disclaims responsibility for any analyses, interpretations, or conclusions.
• Keywords: QUALITY-OF-LIFE; Quality of life; Form submission; Patient-reported outcomes; RTOG 0319; Patient compliance; ONCOLOGY; Health Policy & Services; COGNITIVE DYSFUNCTION; WHOLE-BRAIN RADIOTHERAPY; Public, Environmental & Occupational Health; Delinquent data; CANCER; Health Care Sciences & Services; Life Sciences & Biomedicine; PREVENTION; Neurocognitive testing; CLINICAL-TRIALS; Science & Technology; EXERCISE BEHAVIOR; MEMANTINE

Abstract

PURPOSE: NRG Oncology, part of the National Cancer Institute's National Clinical Trials Network, took efforts to increase patient-reported outcome measures (PROMs) completion and institutional data submission rates within clinical trials. Lack of completion diminishes power to draw conclusions and can be a waste of resources. It is hypothesized that trials with automatic email reminders and past due notifications will have PROM forms submitted more timely with higher patient completion. METHODS: Automatic emails sent to the research associate were added to selected NRG Oncology trials. Comparisons between trials with and without automatic emails were analyzed using Chi-square tests with respect to patient completion and timeliness of form submission rates. Multivariable analyses were conducted using repeated measures generalized estimating equations. If PROMs were not completed, a form providing the reason why was submitted and counted towards form submission. RESULTS: For both disease sites, form submission was significantly higher within 1 month of the form's due date for the studies with automatic emails vs. those without (prostate: 79.7% vs. 75.7%, p < 0.001; breast: 59.2% vs. 31.3%, p < 0.001). No significant differences in patient completion were observed between the breast trials. The prostate trial with automatic emails had significantly higher patient completion but this result was not confirmed in the multivariable analysis. CONCLUSIONS: Although patient completion rates were higher on trials with automatic emails, there may be confounding factors requiring future study. The automatic emails appeared to have increased the timeliness of form submission, thus supporting their continued use on NRG Oncology trials.