Transfusion therapy for sickle cell disease: what's new?

• Type of Material: Article
• Authors: Stella T Chou, University of Pennsylvania; Jeanne Hendrickson, Emory University; Ross Fasano, Emory University
• Language: English
• Date: 2023-06-13
• Publisher: ELSEVIER
• Publication Version: Final Published Version
• Copyright Statement: © 2023 by The American Society of Hematology. Licensed under Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0), permitting only noncommercial, nonderivative use with attribution. All other rights reserved.
• License: Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.1182/bloodadvances.2022009283
• Title of Journal or Parent Work: BLOOD ADVANCES
• Volume: 7
• Issue: 11
• Start Page: 2551
• End Page: 2553
• Keywords: Life Sciences & Biomedicine; Science & Technology; Hematology
• Research Categories: Health Sciences, Medicine and Surgery

Abstract

The American Society of Hematology (ASH) 2020 guidelines for transfusion support for individuals with sickle cell disease (SCD)1 included recommendations on specific indications and administration of transfusion, as well as screening, prevention, and management of alloimmunization, delayed hemolytic transfusion reactions (DHTRs), and iron overload. The ASH Guideline Monitoring Expert Working Group conducted an updated literature search that did not identify new studies that would change the current recommendations.