Survey of Wild Mammal Hosts of Cutaneous Leishmaniasis Parasites in Panamá and Costa Rica

• Type of Material: Article
• Authors: Kadir González, Instituto Conmemorativo Gorgas de Estudios de la Salud; Jose E Calzada, Instituto Conmemorativo Gorgas de Estudios de la Salud; Azael Saldaña, Instituto Conmemorativo Gorgas de Estudios de la Salud; Chystrie A Rigg, Instituto Conmemorativo Gorgas de Estudios de la Salud; Gilbert Alvarado, Universidad de Costa Rica; Bernal Rodríguez-Herrera, Universidad de Costa Rica; Uriel Kitron, Emory University; Gregory H. Adler, University of Wisconsin-Oshkosh; Nicole L. Gottdenker, University of Georgia; Luis Fernando Chaves, Universidad Nacional; Mario Baldi, Universidad Nacional
• Language: English
• Date: 2015-03-14
• Publisher: BioMed Central
• Publication Version: Final Published Version
• Copyright Statement: © 2015 by The Japanese Society of Tropical Medicine
• License: Creative Commons Attribution 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.2149/tmh.2014-30
• Title of Journal or Parent Work: Tropical Medicine and Health
• ISSN: 1348-8945
• Volume: 43
• Issue: 1
• Start Page: 75
• End Page: 78
• Grant/Funding Information: This study was funded by a Gorgas Memorial Research Award of the American Society of Tropical Medicine and Hygiene, NETROPICA Grant 04-N-2010, SENACYT Grant CCP06-040, Emory University, and Nagasaki University (Program for Nurturing Global Leaders in Tropical and Emerging Communicable Diseases).
• Keywords: Leishmania Spp.; zoonotic disease; reservoir
• Research Categories: Agriculture, Animal Pathology; Biology, Parasitology; Environmental Sciences

Abstract

The eco-epidemiology of American cutaneous leishmaniasis (ACL) is driven by animal reservoir species that are a source of infection for sand flies that serve as vectors infecting humans with Leishmania spp parasites. The emergence and re-emergence of this disease across Latin America calls for further studies to identify reservoir species associated with enzootic transmission. Here, we present results from a survey of 52 individuals from 13 wild mammal species at endemic sites in Costa Rica and Panama where ACL mammal hosts have not been previously studied. For Leishmania spp. diagnostics we employed a novel PCR technique using blood samples collected on filter paper. We only found Leishmania spp parasites in one host, the two-toed sloth, Choloepus hoffmanni. Our findings add further support to the role of two-toed sloths as an important ACL reservoir in Central America.