Utility of double inversion recovery MRI in paediatric epilepsy

• Type of Material: Article
• Authors: Bruno Soares, Emory University; Samuel G Porter, Emory University; Amit Saindane, Emory University; Seena Dehkharghani, Emory University; Nilesh K Desai, Emory University
• Language: English
• Date: 2016-01-01
• Publisher: British Institute of Radiology
• Publication Version: Final Published Version
• Copyright Statement: © 2015 The Authors. Published by the British Institute of Radiology.
• Final Published Version (URL): http://dx.doi.org/10.1259/bjr.20150325
• Title of Journal or Parent Work: British Journal of Radiology
• ISSN: 0007-1285
• Volume: 89
• Issue: 1057
• Start Page: 20150325
• End Page: 20150325
• Keywords: Life Sciences & Biomedicine; 3T; BRAIN; FLAIR; MULTIPLE-SCLEROSIS; IDENTIFICATION; TEMPORAL-LOBE EPILEPSY; FOCUS LATERALITY; INTRACORTICAL LESIONS; Radiology, Nuclear Medicine & Medical Imaging; Science & Technology; MATTER; FOCAL CORTICAL DYSPLASIA
• Research Categories: Health Sciences, Radiology; Biology, Neuroscience

Abstract

Detecting focal abnormalities in MRI examinations of children with epilepsy can be a challenging task given the frequently subtle appearance of cortical dysplasia, mesial temporal sclerosis and similar lesions. In this report, we demonstrate the utility of double inversion recovery MRI in the detection of paediatric epileptogenic abnormalities, promoted primarily by increased lesion conspicuity due to complementary suppression of both cerebrospinal fluid and normal white matter signal.