No increased risk of obstructive sleep apnea in Parkinson's disease

• Type of Material: Article
• Authors: Lynn Marie Trotti, Emory University; Donald Bliwise, Emory University
• Language: English
• Date: 2010-10-15
• Publisher: Wiley
• Publication Version: Author Accepted Manuscript (After Peer Review)
• Copyright Statement: Published 2010 Wiley-Liss, Inc.
• Final Published Version (URL): http://onlinelibrary.wiley.com/doi/10.1002/mds.23231/abstract
• Title of Journal or Parent Work: Movement Disorders
• ISSN: 0885-3185
• Volume: 25
• Issue: 13
• Start Page: 2246
• End Page: 2249
• Grant/Funding Information: Dr. Trotti was partially supported by PHS Grant KL2 RR025009 from the Clinical and Translation Science Award program, NIH, National Center for Research Resources, and by NIH grant NS-050595.; Dr. Bliwise was partially supported by NIH grant NS-050595.
• Keywords: Parkinson’s Disease; Excessive Daytime Sleepiness; Obstructive Sleep Apnea
• Research Categories: Biology, Neuroscience

Abstract

Pulmonary function abnormalities in Parkinson’s disease (PD) might predispose patients to obstructive sleep apnea (OSA) and daytime sleepiness. Fifty-five idiopathic PD patients (mean age = 63.9) underwent three consecutive nights of in-laboratory polysomnography on their usual dopaminergic medications. Sleep apnea severity was compared to published, normative, population-based data from the Sleep Heart Health Study. Demographic and clinical data were compared in patients with and without OSA. The apnea-hyponea index (AHI) was stable across nights in PD patients, and was not different between PD patients and normative controls. Epworth Sleepiness Scale scores, Body Mass Index, and snoring did not correlate with AHI. Severity of OSA is stable across multiple nights in PD patients. Rates of OSA in PD are similar to those seen in the general population. Daytime sleepiness, snoring, and obesity may not be helpful in identifying OSA in PD.