In Vivo High-Frequency, Contrast-Enhanced Ultrasonography of Uveal Melanoma in Mice: Imaging Features and Histopathologic Correlations

• Type of Material: Article
• Authors: Qing Zhang, Emory University; Hua Yang, Emory University; Shin Jeong Kang, Emory University; Yanggan Wang, Pediatrics and Children's Healthcare of Atlanta; Geoffrey D. Wang, University of Georgia; Tonya Coulthard, VisualSonics; Hans Grossniklaus, Emory University
• Language: English
• Date: 2011-04
• Publisher: Association for Research in Vision and Ophthalmology, Inc.
• Publication Version: Final Published Version
• Copyright Statement: © Association for Research in Vision and Ophthalmology
• Final Published Version (URL): http://www.iovs.org/content/52/5/2662
• Title of Journal or Parent Work: Investigative Ophthalmology & Visual Science
• Volume: 52
• Issue: 5
• Start Page: 2662
• End Page: 2668
• Grant/Funding Information: Supported in part by National Institutes of Health Grants R01 CA126557 (HEG) and R24 EY017045 (HEG) and by an unrestricted departmental grant from Research to Prevent Blindness, Inc..
• Research Categories: Health Sciences, Opthamology; Health Sciences, Pathology

Abstract

The authors demonstrated that high-frequency, contrast-enhanced ultrasonography is a real-time, noninvasive, and reliable method for in vivo evaluation of experimental intraocular melanoma tumor area and relative blood volume.