Renal failure after placement of an articulating, antibiotic impregnated polymethylmethacrlyate hip spacer

• Type of Material: Article
• Authors: Robert P. Runner, Emory University; Amanda Mener, Emory University; Thomas L Bradbury, Emory University
• Language: English
• Date: 2018-03-01
• Publisher: Elsevier
• Publication Version: Final Published Version
• Copyright Statement: © 2017 The Authors. Published by Elsevier Inc. on behalf of The American Association of Hip and Knee Surgeons.
• License: Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.1016/j.artd.2017.02.005
• Title of Journal or Parent Work: Arthroplasty Today
• ISSN: 2352-3441
• Volume: 4
• Issue: 1
• Start Page: 51
• End Page: 57
• Keywords: Antibiotic spacer; Antibiotic impregnated cement; Acute renal failure; Septic arthritis; Hemodialysis
• Research Categories: Health Sciences, Rehabilitation and Therapy; Health Sciences, Medicine and Surgery

Abstract

A 58-year-old male presented with native joint septic arthritis of the hip and osteomyelitis. After treatment with an articulating antibiotic spacer, he developed acute renal failure requiring dialysis. He continued to have elevated serum tobramycin levels exclusively from the antibiotic spacer elution as no intravenous tobramycin was used. Subsequent explantation was required to correct his renal failure. Although renal failure after antibiotic impregnated cement placement is rare, the risk of this potential complication should be considered preoperatively and in the postoperative management of these patients.