Advances in Clinical and Basic Science of Coagulation: Illustrated abstracts of the 9th Chapel Hill Symposium on Hemostasis.

• Type of Material: Article
• Authors: Wolfgang Bergmeier, University of North Carolina; Silvio Antoniak, University of North Carolina; Edward M. Conway, UBC Centre for Blood Research; Cécile V. Denis, INSERM U1176; Lindsey A. George, University of Pennsylvania; Berend Isermann, University Magdeburg; Nigel S. Key, University of North Carolina; Sriram Krishnaswamy, University of Pennsylvania; Wilbur Lam, Emory University; David Lillicrap, Queen's University; Jian Liu, University of North Carolina; Mark R. Looney, University of California; José A. López, University of Washington; Coen Maas, University Medical Center; Flora Peyvandi, University of IRCCS Maggiore; Wolfram Ruf, The Scripps Research Institute; Anil K. Sood, University of Texas; Henri H. Versteeg, Leiden University; Alisa S. Wolberg, University of North Carolina; Pancras C. Wong, Bristol‐Meyers Squibb; Jeremy P. Wood, University of Kentucky; Hartmut Weiler, Blood Center of Wisconsin
• Language: English
• Date: 2018-07
• Publisher: Wiley
• Publication Version: Final Published Version
• Copyright Statement: © 2018 The Authors. Research and Practice in Thrombosis and Haemostasis published by Wiley Periodicals, Inc on behalf of International Society on Thrombosis and Haemostasis.
• License: Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.1002/rth2.12095
• Title of Journal or Parent Work: Research and Practice in Thrombosis and Haemostasis
• ISSN: 2475-0379
• Volume: 2
• Issue: 3
• Start Page: 407
• End Page: 428
• Research Categories: Chemistry, Biochemistry; Health Sciences, Medicine and Surgery; Health Sciences, Pathology

Abstract

This 9th Symposium on Hemostasis is an international scientific meeting held biannually in Chapel Hill, North Carolina. The meeting is in large measure the result of the close friendship between the late Dr. Harold R. Roberts of UNC Chapel Hill and Dr. Ulla Hedner of Novo Nordisk. When Novo Nordisk was developing the hemophilia therapy that would become NovoSeven, they sponsored a series of meetings to understand the basic biology and clinical applications of factor VIIa. The first meeting in Chapel Hill was held April 4-6, 2002 with Dr. Roberts as the organizer. Over the years, the conference emphasis has expanded from discussions of factor VIIa and tissue factor to additional topics in hemostasis and thrombosis. This year's meeting includes presentations by internationally renowned speakers that discuss the state-of-the-art on an array of important topics, including von Willebrand factor, engineering advances, coagulation and disease, tissue factor biology, therapeutic advances, and basic clotting factor biology. Included in this review article are illustrated abstracts provided by our speakers, which highlight the main conclusions of each invited talk. This will be the first meeting without Dr. Roberts in attendance, yet his commitment to excellent science and his focus on turning science to patient care are pervasively reflected in the presentations by our speakers.