Clinical Outcomes of Critically III Patients with COVID-19 by Race.

• Type of Material: Article
• Authors: Fahad Marmarchi, Emory University; Michael Liu, Emory University; Srikant Rangaraju, Emory University; Sara C. Auld, Emory University; Maria Christina Creel-Bulos, Emory University; Christine Kempton, Emory University; Milad Sharifpour, Emory University; Manila Gaddh, Emory University; Roman M Sniecinski, Emory University; Cheryl L. Maier, Emory University; Fadi Nahab, Emory University; Gregory Martin, Emory University
• Language: English
• Date: 2021-01-19
• Publisher: Springer
• Publication Version: Final Published Version
• Copyright Statement: © W. Montague Cobb-NMA Health Institute 2021
• License: Creative Commons Attribution 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.1007/s40615-021-00966-0
• Title of Journal or Parent Work: J Racial Ethn Health Disparities
• Grant/Funding Information: This study was supported by Grant K23 AL134182 from the National Institute of Health/National Institute of Allergy and Infectious Disease. Sara C. Auld MD, MSc.
• Keywords: COVID-19; Outcomes; African American; Race; Mortality
• Research Categories: Health Sciences, Public Health; Biology, Virology

Abstract

BACKGROUND: Studies of COVID-19 have shown that African Americans have been affected by the virus at a higher rate compared to other races. This cohort study investigated comorbidities and clinical outcomes by race among COVID-19 patients admitted to the intensive care unit. METHODS: This is a case series of critically ill patients admitted with COVID-19 to an academic healthcare system in Atlanta, Georgia. The study included all critically ill hospitalized patients between March 6, 2020, and May 5, 2020. Clinical outcomes during hospitalization included mechanical ventilation, renal replacement therapy, and mortality stratified by race. RESULTS: Of 288 patients included (mean age, 63 ± 16 years; 45% female), 210 (73%) were African American. African Americans had significantly higher rates of comorbidities compared to other races, including hypertension (80% vs 59%, P = 0.001), diabetes (49% vs 34%, P = 0.026), and mean BMI (33 kg/m2 vs 28 kg/m2, P < 0.001). Despite African Americans requiring continuous renal replacement therapy during hospitalization at higher rates than other races (27% vs 13%, P = 0.011), rates of intubation, intensive care unit length of stay, and overall mortality (30% vs 24%, P = 0.307) were similar. CONCLUSION: This racially diverse series of critically ill COVID-19 patients shows that despite higher rates of comorbidities at hospital admission in African Americans compared with other races, there was no significant difference in mortality.