Developmental outcomes of Down syndrome and Dandy-Walker malformation

• Type of Material: Article
• Authors: Kaitlin Love, Florida State University; Lillie Huddleston, Emory University; Pat Olney, Emory University; David Wrubel, Emory University; Jeannie Visootsak, Emory University
• Language: English
• Date: 2011-01-01
• Publisher: IOS Press
• Publication Version: Author Accepted Manuscript (After Peer Review)
• Copyright Statement: © 2011 – IOS Press and the authors. All rights reserved
• Final Published Version (URL): http://iospress.metapress.com/content/u621044872j0206k/?issue=3&genre=article&spage=405&issn=1304-2580&volume=9
• Title of Journal or Parent Work: Journal of Pediatric Neurology
• ISSN: 1304-2580
• Volume: 9
• Issue: 3
• Start Page: 405
• End Page: 408
• Keywords: developmental outcomes; Down syndrome; Dandy-Walker syndrome
• Research Categories: Biology, Neuroscience

Abstract

Dandy-Walker syndrome (DWS), or Dandy-Walker complex, is a congenital brain malformation of the posterior fossa, typically resulting in developmental delay and cognitive disability. The co-occurrence of Down syndrome (DS) and DWS is relatively uncommon; thus, its impact on developmental outcomes has not been fully elucidated. Herein, we report a case of a 37-month-old child with DS and DWS, who is functioning at the following age-equivalent: gross motor at a 9-mo level, fine motor 6 mo, expressive language 14 mo, receptive language 9 mo. As such, it is important to determine how the DWS influences developmental outcomes, and appreciate the importance of early interventional therapy.