cIMPACT-NOW (the consortium to inform molecular and practical approaches to CNS tumor taxonomy): a new initiative in advancing nervous system tumor classification

• Type of Material: Article
• Authors: Daniel Brat, Emory University; David N Louis, Massachusetts General Hospital; Ken Aldape, Princess Margaret Hospital; Daniel Capper, Ruprecht Karls University Heidelberg; David W Ellison, St Jude Childrens Res Hosp; Cynthia Hawkins, University of Toronto; Werner Paulus, University Hospital Munster; Arie Perry, University of California San Francisco; Guido Reifenberger, Heinrich Heine University; Dominique Figarella-Branger, Aix Marseille University; Pieter Wesseling, Vrije University Amsterdam Medical Center; Tracy T Batchelor, University of Calgary; Gregory J Cairncross, University of Calgary; Stefan M Pfister, German Cancer Research Center (DKFZ) Heidelberg; Stefan Rutkowski, University Medical Center Hamburg‐Eppendorf; Michael Weller, Univ Med Ctr Hamburg Eppendorf; Wolfhang Wick, German Cancer Consortium (DKTK) Core Center Heidelberg; Andreas von Deimling, Ruprecht‐Karls‐University, Heidelberg
• Language: English
• Date: 2017-11-01
• Publisher: WILEY
• Publication Version: Final Published Version
• Copyright Statement: © 2016 International Society of Neuropathology
• License: Creative Commons Attribution 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.1111/bpa.12457
• Title of Journal or Parent Work: BRAIN PATHOLOGY
• Volume: 27
• Issue: 6
• Start Page: 851
• End Page: 852
• Keywords: Neurosciences; Life Sciences & Biomedicine; Science & Technology; Pathology; Clinical Neurology; Neurosciences & Neurology
• Research Categories: Health Sciences, Oncology; Health Sciences, Pathology

Abstract

The 2016 World Health Organization Classification of Tumors of the Central Nervous System (2016 CNS WHO) is a major shift in the way neuropathologists analyze and diagnose brain tumors as it incorporates molecular and histological information together to define many entities 1. While the 2016 CNS WHO thereby facilitates more precise diagnosis of well‐understood entities and clearer designation of less‐understood entities, it also presents a number of practical challenges for neuropathologists, requiring substantial shifts in their day‐to‐day practices 2. Nonetheless, neuropathologists will learn the system readily over time, and will adapt as needed to the new requirements.