Long-lasting insecticide-treated house screens and targeted treatment of productive breeding-sites for dengue vector control in Acapulco, Mexico

• Type of Material: Article
• Authors: Azael Che-Mendoza, Gobierno del Estado de Yucatán; Guillermo Guillermo-May, Universidad Autónoma de Yucatán; Josué Herrera-Bojórquez, Universidad Autónoma de Yucatán; Mario Barrera-Pérez, Universidad Autónoma de Yucatán; Felipe Dzul-Manzanilla, Servicios Estatales de Salud de Guerrero; Cipriano Gutierrez-Castro, Servicios Estatales de Salud de Guerrero; Juan I. Arredondo-Jiménez, Secretaria de Salud, Mexico; Gustavo Sánchez-Tejeda, Secretaria de Salud, Mexico; Gonzalo Vazquez Prokopec, Emory University; Hilary Ranson, Liverpool School of Tropical Medicine; Audrey Lenhart, Emory University; Johannes Sommerfeld, World Health Organization; Philip J. McCall, Liverpool School of Tropical Medicine; Axel Kroeger, World Health Organization; Pablo Manrique-Saide, Universidad Autónoma de Yucatán
• Language: English
• Date: 2015-02-01
• Publisher: Oxford University Press (OUP): Policy B - Oxford Open Option B
• Publication Version: Final Published Version
• Copyright Statement: © The author 2015. The World Health Organization has granted Oxford University Press permission for the reproduction of this article.
• License: Creative Commons Attribution 3.0 IGO License
• Final Published Version (URL): http://dx.doi.org/10.1093/trstmh/tru189
• Title of Journal or Parent Work: Transactions of The Royal Society of Tropical Medicine and Hygiene
• ISSN: 0035-9203
• Volume: 109
• Issue: 2
• Start Page: 106
• End Page: 115
• Grant/Funding Information: This investigation received financial support from the UNICEF/UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases (TDR) with the aid of a grant from the International Development Research Centre (IDRC), Ottawa, Canada.; We also thank FOMIX CONACYT-Guerrero for the financial support of the Project ‘Control Integrado de Aedes aegypti con estrategias y herramientas innovadoras en una zona de alto riesgo para la transmisión del dengue en Guerrero, México’ (Project GUE-2008-02-108686).
• Keywords: Control; Dengue; Disease Reservoirs; Sentinel Surveillance; Patient Acceptance of Health Care; Water Supply; Urban Health; Animals; Health Knowledge, Attitudes, Practice; Aedes aegypti; Community Health Services; LLIS; Insecticides; Aedes; Humans; Insecticide-Treated Bednets; Dengue Virus; Mexico; Mosquito Control; Seasons; Cluster Analysis; Targeted treatment
• Research Categories: Environmental Sciences; Health Sciences, Public Health; Biology, Virology

Abstract

Background: Long-lasting insecticidal net screens (LLIS) fitted to domestic windows and doors in combination with targeted treatment (TT) of the most productive Aedes aegypti breeding sites were evaluated for their impact on dengue vector indices in a cluster-randomised trial in Mexico between 2011 and 2013. Methods: Sequentially over 2 years, LLIS and TT were deployed in 10 treatment clusters (100 houses/cluster) and followed up over 24 months. Cross-sectional surveys quantified infestations of adult mosquitoes, immature stages at baseline (pre-intervention) and in four post-intervention samples at 6-monthly intervals. Identical surveys were carried out in 10 control clusters that received no treatment. Results: LLIS clusters had significantly lower infestations compared to control clusters at 5 and 12 months after installation, as measured by adult (male and female) and pupal-based vector indices. After addition of TT to the intervention houses in intervention clusters, indices remained significantly lower in the treated clusters until 18 (immature and adult stage indices) and 24 months (adult indices only) post-intervention. Conclusions: These safe, simple affordable vector control tools were well-accepted by study participants and are potentially suitable in many regions at risk from dengue worldwide.